DYDC1 and DPY30

Data Source:
HPRD (two hybrid)

		DYDC1	DPY30
Description		DPY30 domain containing 1	dpy-30 histone methyltransferase complex regulatory subunit
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region MLL3/4 Complex Set1C/COMPASS Complex	Chromosome, Telomeric Region Nucleus Nucleoplasm Golgi Apparatus Trans-Golgi Network Histone Methyltransferase Complex MLL3/4 Complex Set1C/COMPASS Complex
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Chromatin Silencing At Telomere Histone H3-K4 Methylation	Chromatin Silencing At Telomere Endosomal Transport Regulation Of Megakaryocyte Differentiation Histone H3-K4 Methylation
Pathways			PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31451708)	Inflammatory biomarkers ( 24182552) Interleukin-18 levels ( 31584380) Male-pattern baldness ( 28196072)
Interacting Genes		33 interacting genes: ARNT2 CCHCR1 CCNC CEP57L1 DPY30 ENKD1 HDAC4 HGS KRT75 LMO2 LNX1 MID2 MOS NME5 PDZD4 PIK3R2 PKN1 POU6F2 PPP2R5D PSMA1 TCHP TEAD4 TFPT TLE5 TSGA10IP TXLNB TXNDC9 USHBP1 USP2 VPS37C VPS9D1 WAC ZGPAT	33 interacting genes: AK8 AKAP14 ARFGEF1 ASH2L BCAS4 BEND3 CDK17 CFAP91 CHMP2B CREB3L3 DYDC1 DYDC2 FAM136A GPATCH2 GTF2I H3-4 ICA1L KMT2C MRFAP1 OTX1 PRPF3 PRRC2B PSMC3 PSMD14 PXN RSPH3 SETD1A TMCC2 TSPY10 TSPY2 TSPY3 UBC ZFYVE19
Entrez ID		143241	84661
HPRD ID		14062	17434
Ensembl ID		ENSG00000170788	ENSG00000162961
Uniprot IDs		Q8WWB3	B4DIS3 Q9C005
PDB IDs			3G36 4RIQ 4RT4 4RTA 6E2H 6PWV
Enriched GO Terms of Interacting Partners?
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