STK35 and PDLIM1

Data Source:
HPRD (in vitro, two hybrid)

		STK35	PDLIM1
Description		serine/threonine kinase 35	PDZ and LIM domain 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Nuclear Body	Stress Fiber Transcription Regulator Complex Cytoplasm Cytoskeleton Adherens Junction Focal Adhesion Z Disc Filamentous Actin
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Transcription Coactivator Activity Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Protein Phosphorylation Meiotic Cell Cycle	Response To Hypoxia Regulation Of Transcription By RNA Polymerase II Response To Oxidative Stress Heart Development Fibroblast Migration Maintenance Of Cell Polarity Actin Cytoskeleton Organization Establishment Or Maintenance Of Actin Cytoskeleton Polarity Stress Fiber Assembly Positive Regulation Of Transcription, DNA-templated Muscle Structure Development Cell-cell Adhesion
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Adult body size ( 32376654) Early spontaneous preterm birth ( 31194736) Immune response to measles-mumps-rubella vaccine ( 24811271) Plateletcrit ( 32888494) Refractive error ( 32231278)	Hemoglobin ( 32888494) Mean platelet volume ( 32888494 27863252) Suicide risk ( 21041247) White blood cell count ( 32888494)
Interacting Genes		6 interacting genes: BMPR1B OSBPL3 PDLIM1 SMAD4 SMURF1 TGFBR1	14 interacting genes: ACTN1 ACTN2 ACTN4 AGK GFAP MAPK6 PGS1 PITX2 PTGER4 RLIM RPS6KA5 STK35 SUPT4H1 VIM
Entrez ID		140901	9124
HPRD ID		11612	09326
Ensembl ID		ENSG00000125834	ENSG00000107438
Uniprot IDs		Q8TDR2	O00151 V9HW92
PDB IDs			1X62 2PKT
Enriched GO Terms of Interacting Partners?
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