NACC2 and EPS8

Data Source:
BioGRID (two hybrid)

		NACC2	EPS8
Description		NACC family member 2	epidermal growth factor receptor pathway substrate 8
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleolus Mitochondrion	Plasma Membrane Cell Cortex Growth Cone Vesicle Stereocilium Ruffle Membrane Synapse Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Protein-containing Complex Binding	Actin Binding Protein Binding Small GTPase Binding Signaling Adaptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Cellular Protein-containing Complex Localization Negative Regulation Of Transcription, DNA-templated Protein Homooligomerization Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle By Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Rho Protein Signal Transduction Regulation Of Cell Shape Exit From Mitosis Rac Protein Signal Transduction Regulation Of Actin Filament Length Regulation Of Rho Protein Signal Transduction Dendritic Cell Migration Regulation Of Catalytic Activity Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Actin Crosslink Formation Actin Polymerization-dependent Cell Motility Positive Regulation Of Ruffle Assembly
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) SjÃ¶gren's syndrome ( 28076899) Ulcerative colitis ( 28067908)	Metabolite levels ( 23823483) Protein quantitative trait loci ( 18464913)
Interacting Genes		5 interacting genes: EPS8 HDAC2 MTA1 MTA2 MTA3	61 interacting genes: ABI1 ACTA1 ADAM22 AIMP2 ALDH7A1 ARMC1 BAIAP2 BCKDK BLOC1S6 BORCS6 BYSL C19orf25 C6orf141 C8orf33 CASK CBL CCDC85B CSNK2B CTNNA3 CXCL2 DNALI1 DVL1 EGFR GOLGA8EP GRB2 GULP1 HNRNPC HOOK2 INPP5J ITGB1 ITGB3 ITGB5 ITSN2 MAP1LC3B MAP3K11 MRPL20 MYO15A NACC2 NFKB2 PCM1 PROSER2 RCAN3 RFXAP RSPH14 RUNX1T1 SCRN3 SERPINA5 SF3B3 SHB SHC1 SLC27A4 SMARCE1 SOS1 SRC TDP2 TEX28 TPRN USP6NL XAGE2 XRCC6 ZZZ3
Entrez ID		138151	2059
HPRD ID		09831	02563
Ensembl ID		ENSG00000148411	ENSG00000151491
Uniprot IDs		A0A024R8I0 Q96BF6	B4E3T6 Q12929
PDB IDs			2E8M
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?