FLACC1 and TCL1A

Data Source:
BioGRID (two hybrid)

		FLACC1	TCL1A
Description		flagellum associated containing coiled-coil domains 1	TCL1 family AKT coactivator A
Image		No pdb structure
GO Annotations	Cellular Component	Outer Dense Fiber Cellular_component Cytoplasm Sperm Fibrous Sheath Sperm Flagellum	Nucleoplasm Endoplasmic Reticulum Cytosol Protein-containing Complex
	Molecular Function	Molecular_function Protein Binding	Protein Binding Protein Kinase Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity
	Biological Process		Multicellular Organism Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Apoptotic Process Cellular Response To Tumor Necrosis Factor Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways
Drugs
Diseases
GWAS			Adverse response to aromatase inhibitors ( 20876420) Mosaic loss of chromosome Y ( 27064253) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Plateletcrit ( 32888494) Refractive error ( 32231278)
Interacting Genes		22 interacting genes: ATP6V1H BLK CRK DISC1 DVL3 FAM90A1 INO80B LGALS14 LONRF1 PRPF31 SPG21 SSX2 SSX2B SSX4 SSX4B STK16 SULT2B1 TCL1A TEPSIN TRIM41 TXNDC5 YES1	38 interacting genes: AKT1 AKT2 AKT3 ATM CADPS CALCOCO2 CARD9 CASP8AP2 CCDC13 CEP55 DDIT4L DNMT3A FLACC1 GOLGA2 H2AW INCA1 LNX1 LNX2 LSM3 NFKBIA NFKBID NIF3L1 NTAQ1 PPP1R13B PRTFDC1 REL TAX1BP1 TCF4 TEPSIN TNKS TP53BP2 TRAF1 TRAF2 TRMT61A TTC33 TXLNA TXLNB WDR47
Entrez ID		130540	8115
HPRD ID		12444	01744
Ensembl ID		ENSG00000155749	ENSG00000100721
Uniprot IDs		A8K8B8 Q96Q35	A0A024R6G5 P56279
PDB IDs			1JSG
Enriched GO Terms of Interacting Partners?
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