TAF8 and TAF4

Data Source:
HPRD (in vivo, in vitro)

		TAF8	TAF4
Description		TATA-box binding protein associated factor 8	TATA-box binding protein associated factor 4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Perinuclear Region Of Cytoplasm	Chromatin Nucleoplasm Transcription Factor TFIID Complex Cytosol Protein-containing Complex Transcription Factor TFTC Complex MLL1 Complex
	Molecular Function	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity	Core Promoter Sequence-specific DNA Binding DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Aryl Hydrocarbon Receptor Binding Protein Heterodimerization Activity
	Biological Process	DNA-templated Transcription Open Complex Formation Inner Cell Mass Cell Proliferation Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation SnRNA Transcription By RNA Polymerase II Regulation Of Fat Cell Differentiation Maintenance Of Protein Location In Nucleus	Ovarian Follicle Development DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Viral Process Regulation Of Signal Transduction By P53 Class Mediator
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (number of eye fixations) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (responsive search score) ( 26242244) HDL cholesterol levels ( 28334899) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Neutrophil percentage of white cells ( 32888494)	Body mass index ( 28892062) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Red blood cell count ( 32888494) Response to fenofibrate (LDL cholesterol levels) ( 27002377)
Interacting Genes		13 interacting genes: H3-4 KPNA2 KPNB1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF6 TAF7 TAF9	22 interacting genes: AHR ATF7 CBX3 CBX5 CREM GTF2A1 GTF2A2 H3-4 HTT JUN SP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF5 TAF6 TAF7 TAF8 TAF9 TCF12
Entrez ID		129685	6874
HPRD ID		18167	11797
Ensembl ID		ENSG00000137413	ENSG00000130699
Uniprot IDs		Q7Z7C8	O00268
PDB IDs		4WV4 4WV6 5FUR 6MZC 6MZL 6MZM	1H3O 2P6V 6MZC 6MZD 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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