DUSP15 and PTK7

Data Source:
BioGRID (two hybrid)

		DUSP15	PTK7
Description		dual specificity phosphatase 15	protein tyrosine kinase 7 (inactive)
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GO Annotations	Cellular Component	Cytosol Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Protein Kinase Activity Protein Binding ATP Binding Cell Adhesion Molecule Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway
	Biological Process	Transforming Growth Factor Beta Receptor Signaling Pathway Dephosphorylation Peptidyl-tyrosine Dephosphorylation Regulation Of Cell Population Proliferation Positive Regulation Of JNK Cascade	Establishment Of Planar Polarity Kidney Development Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Regulation Of Canonical Wnt Signaling Pathway Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Coronary artery disease ( 29212778)
Interacting Genes		2 interacting genes: IGF1R PTK7	38 interacting genes: CDC14A CLNK CTDSP2 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 DUSP29 ERBB2 ILKAP KRTAP1-3 KRTAP10-8 MDFI MTMR1 MTMR10 MTMR6 MTMR9 MTUS2 NBPF19 NOTCH2NLA PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR STYX TPTE TPTE2
Entrez ID		128853	5754
HPRD ID		13252	03534
Ensembl ID		ENSG00000149599	ENSG00000112655
Uniprot IDs		Q9H1R2	Q13308
PDB IDs		1YZ4	6VG3
Enriched GO Terms of Interacting Partners?
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