ADH5 and SNTA1

Data Source:
BioGRID (unspecified method)

		ADH5	SNTA1
Description		alcohol dehydrogenase 5 (class III), chi polypeptide	syntrophin alpha 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Extracellular Exosome	Intracellular Anatomical Structure Cytoplasm Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Lateral Plasma Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Synapse Postsynaptic Membrane
	Molecular Function	Alcohol Dehydrogenase Activity, Zinc-dependent Fatty Acid Binding Zinc Ion Binding Electron Transfer Activity Formaldehyde Dehydrogenase Activity Identical Protein Binding S-(hydroxymethyl)glutathione Dehydrogenase Activity S-(hydroxymethyl)glutathione Dehydrogenase NADP Activity S-(hydroxymethyl)glutathione Dehydrogenase NAD Activity	Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Ion Channel Binding Nitric-oxide Synthase Binding ATPase Binding
	Biological Process	Retinoid Metabolic Process Respiratory System Process Ethanol Oxidation Fatty Acid Omega-oxidation Peptidyl-cysteine S-nitrosylation Electron Transport Chain Response To Lipopolysaccharide Positive Regulation Of Blood Pressure Formaldehyde Catabolic Process Response To Nitrosative Stress Response To Redox State	Regulation Of Heart Rate Regulation Of Vasoconstriction By Circulating Norepinephrine Muscle Contraction Neuromuscular Junction Development Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport
Pathways		Ethanol oxidation
Drugs		NADH Lauric acid 12-Hydroxydodecanoic Acid S-Hydroxymethyl Glutathione
Diseases			Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS		Alcohol consumption ( 28937693) Alcohol consumption in current drinkers ( 28937693) Alcohol dependence ( 23456092) Blood protein levels ( 30072576) HDL cholesterol ( 24097068 25961943) HDL cholesterol levels ( 28334899) Obesity-related traits ( 23251661) Plateletcrit ( 32888494) Regular attendance at a pub or social club ( 29970889)	HDL cholesterol x physical activity interaction (1df test) ( 30670697) HDL cholesterol x physical activity interaction (2df test) ( 30670697)
Interacting Genes		9 interacting genes: APP ARNT CHD3 CSNK2B ESRRA PRDX1 SLC66A2 SNTA1 VTN	74 interacting genes: ABCA1 ABCC4 ACTA2 ADAMTS6 ADGRB1 ADGRB2 ADGRB3 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA DTNB F8A1 FABP1 FAM189B GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 RPS6KA1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TLX3 TRA TRBV12-3 UTRN XRCC6
Entrez ID		128	6640
HPRD ID		00064	03009
Ensembl ID		ENSG00000197894	ENSG00000101400
Uniprot IDs		P11766 Q6IRT1	Q13424
PDB IDs		1M6H 1M6W 1MA0 1MC5 1MP0 1TEH 2FZE 2FZW 3QJ5
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?