RNF19B and NIPAL4

Data Source:
BioGRID (two hybrid)

		RNF19B	NIPAL4
Description		ring finger protein 19B	NIPA like domain containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Cytolytic Granule	Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Magnesium Ion Transmembrane Transporter Activity
	Biological Process	Protein Polyubiquitination Adaptive Immune Response Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Natural Killer Cell Mediated Cytotoxicity Protein Autoubiquitination	Magnesium Ion Transport Magnesium Ion Transmembrane Transport
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Miscellaneous transport and binding events
Drugs
Diseases			Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
GWAS		Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)	Asthma ( 31959851)
Interacting Genes		31 interacting genes: AP1M1 APOL3 ASGR1 CDIPT CLEC1A DHODH FDPS GIMAP5 GOSR2 ICMT MEST MFSD5 MS4A1 NIPAL4 PPP1CC RAP1GDS1 SACM1L SEC22A SEC23A SELENOK SLC30A3 TAP1 TMEM100 TMEM120B TMEM208 TMEM31 TNF TSPAN2 UBE2D2 UBE2D3 UBE2L3	15 interacting genes: ACKR2 CLDN7 CMTM2 COMT FFAR2 GJB1 GPR152 HHLA2 IL10RA LHFPL5 RNF185 RNF19B SSMEM1 TM4SF18 TRHR
Entrez ID		127544	348938
HPRD ID		13725	19424
Ensembl ID		ENSG00000116514	ENSG00000172548
Uniprot IDs		Q6ZMZ0	Q0D2K0
PDB IDs
Enriched GO Terms of Interacting Partners?
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