TMEM52B and VAMP3

Data Source:
BioGRID (two hybrid)

		TMEM52B	VAMP3
Description		transmembrane protein 52B	vesicle associated membrane protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Extracellular Exosome	Early Endosome Cytosol Plasma Membrane Cell Surface Integral Component Of Membrane Apical Plasma Membrane Transport Vesicle Clathrin-coated Vesicle Secretory Granule Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Phagocytic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Neuron Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane
	Molecular Function	Molecular_function Protein Binding	SNAP Receptor Activity Protein Binding Syntaxin-1 Binding Syntaxin Binding
	Biological Process	Biological_process	Positive Regulation Of Receptor Recycling Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Positive Regulation Of Immunoglobulin Production Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Substrate Adhesion-dependent Cell Spreading SNARE Complex Assembly Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Membrane Organization Membrane Fusion Protein-containing Complex Assembly Mucus Secretion Cellular Response To Interferon-gamma Negative Regulation Of Secretion By Cell Regulation Of Histamine Secretion By Mast Cell
Pathways			ER-Phagosome pathway Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Morning vs. evening chronotype ( 26835600) Periodontal microbiota ( 22699663) Ulcerative colitis ( 28067908)
Interacting Genes		68 interacting genes: ALG3 APOD APOL2 APOL3 BET1 BTN2A2 C1GALT1 C3orf52 CLDN19 CLDN4 CNIH1 CNIH3 CSGALNACT2 DNAJC30 EMD FXYD3 GAST GPR25 GPR37L1 IGFBP5 INSIG2 ITGAM JAGN1 LHFPL5 LPAR3 LTC4S MAL MARCHF2 MIP MS4A13 NINJ2 NRM NSG1 ORMDL1 PEDS1-UBE2V1 PGAP2 PLN PLP1 RTP2 SEC22A SERP1 SLC30A2 SLC30A8 SLC35A4 SLC35B4 SLC38A7 SMIM1 TF TMEM100 TMEM107 TMEM109 TMEM128 TMEM147 TMEM14C TMEM203 TMEM218 TMEM267 TMEM50B TMEM54 TMEM60 TMEM86B TMEM97 TMUB2 TRAM1L1 TRARG1 VAMP3 VAMP5 ZDHHC15	63 interacting genes: ACAP1 AHNAK2 AIG1 APP AQP6 ARL13B BCAP31 BCL2L13 BIK BSCL2 BSND CD79A CIAO2A CLDN7 CLEC14A COMT DDB1 DNAJC5 EBP ELOVL4 ERGIC3 FAM174A FAM209A FAM210B GORAB GPX8 IKBKG KCNK5 LHFPL5 LMNA MGST2 MGST3 NELFE NEMP1 PDZK1IP1 PLEKHO1 PTGES RETREG3 RMDN3 SAR1A SCN3B SLC10A1 SLC16A2 SNAP23 SNAP29 STX16 STX1A STX2 STX3 STX4 TM4SF19 TM4SF20 TMEM237 TMEM31 TMEM35A TMEM52B TMEM86B TMPPE TMX2 VAMP2 VAMP8 VEGFD VSIR
Entrez ID		120939	9341
HPRD ID		08709	04711
Ensembl ID		ENSG00000165685	ENSG00000049245
Uniprot IDs		Q4KMG9	Q15836 Q6FGG2
PDB IDs
Enriched GO Terms of Interacting Partners?
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