ADD2 and RPH3A

Data Source:
HPRD (in vitro)

		ADD2	RPH3A
Description		adducin 2	rabphilin 3A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane F-actin Capping Protein Complex Postsynaptic Density Cytoplasmic Vesicle Plasma Membrane Raft	Golgi Apparatus Cytosol Synaptic Vesicle Extrinsic Component Of Membrane Secretory Granule Synaptic Vesicle Membrane Protein-containing Complex Neuron Projection Dendritic Spine Synapse Postsynaptic Membrane
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Calmodulin Binding Protein Kinase Binding Spectrin Binding Protein Homodimerization Activity Protein Heterodimerization Activity Actin Filament Binding	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Zinc Ion Binding Selenium Binding Phosphate Ion Binding Protein-containing Complex Binding Inositol 1,4,5 Trisphosphate Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Synapse Assembly Actin Cytoskeleton Organization Hemopoiesis Positive Regulation Of Protein Binding Leukocyte Migration Leukocyte Tethering Or Rolling Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Transmembrane Transport Protein-containing Complex Assembly	Intracellular Protein Transport Spontaneous Neurotransmitter Secretion
Pathways		Miscellaneous transport and binding events
Drugs
Diseases
GWAS		Acne (severe) ( 24927181)	Alcohol consumption (max-drinks) ( 29460428) Apolipoprotein B levels ( 32203549) Body mass index ( 26426971) Chloride levels ( 29403010) Coronary artery disease ( 32469254) LDL cholesterol levels ( 32203549) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Low density lipoprotein cholesterol levels ( 32154731 29403010) Low HDL-cholesterol levels ( 31006500) Platelet count ( 22139419) Serum uric acid levels ( 32514006) Urate levels ( 31578528)
Interacting Genes		8 interacting genes: ADD1 APP CALM1 FYN PRKACA PRKCD PTPRZ1 RPH3A	12 interacting genes: ADD2 CASK GCH1 MYO5A NRXN1 RAB15 RAB27A RAB27B RAB3A RAB3B RAB8A YWHAH
Entrez ID		119	22895
HPRD ID		00037	15273
Ensembl ID		ENSG00000075340	ENSG00000089169
Uniprot IDs		P35612 Q05DK5	A0A024RBK6 Q9Y2J0
PDB IDs
Enriched GO Terms of Interacting Partners?
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