AP1S1 and AP1G1

Data Source:
BioGRID (biochemical, affinity chromatography technology)
HPRD (two hybrid)

		AP1S1	AP1G1
Description		adaptor related protein complex 1 subunit sigma 1	adaptor related protein complex 1 subunit gamma 1
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GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin-coated Pit Membrane AP-1 Adaptor Complex Cytoplasmic Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function		Protein Binding Kinesin Binding GTP-dependent Protein Binding Small GTPase Binding Clathrin Adaptor Activity Cargo Adaptor Activity
	Biological Process	Intracellular Protein Transport Receptor-mediated Endocytosis Response To Virus Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus	Intracellular Protein Transport Golgi To Vacuole Transport Receptor-mediated Endocytosis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Defense Response To Virus By Virus Golgi To Lysosome Transport
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Adult body size ( 32376654)	General cognitive ability ( 29844566) HDL cholesterol levels ( 32203549) Post bronchodilator FEV1 ( 26634245) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)
Interacting Genes		6 interacting genes: AP1G1 AP1G2 AP1M2 AP2A2 PICK1 RHOU	27 interacting genes: AAGAB AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 ARFRP1 BAALC CCDC91 CLINT1 CLTC DNER EPS15 HEATR5B KIF13A MAP1A PSEN2 RABEP1 RABGEF1 SNX9 SPTB SYNRG SYP UBL7 ZNF512B
Entrez ID		1174	164
HPRD ID		04635	04637
Ensembl ID		ENSG00000106367	ENSG00000166747
Uniprot IDs		A0A024QYT6 P61966	A0A140VJE7 O43747 Q8IY97
PDB IDs		4P6Z	1IU1
Enriched GO Terms of Interacting Partners?
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