CKS2 and UNC119

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CKS2	UNC119
Description		CDC28 protein kinase regulatory subunit 2	unc-119 lipid binding chaperone
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GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex SCF Ubiquitin Ligase Complex	Spindle Pole Centrosome Cytosol Intercellular Bridge Synapse Spindle Midzone
	Molecular Function	Chromatin Binding Protein Binding Protein Kinase Binding Histone Binding Ubiquitin Binding Cyclin-dependent Protein Serine/threonine Kinase Activator Activity	Protein Binding Lipid Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Meiosis I Regulation Of Mitotic Cell Cycle Cell Population Proliferation Mitotic Cell Cycle Phase Transition Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Division	Mitotic Cytokinesis Endocytosis Chemical Synaptic Transmission Nervous System Development Visual Perception Phototransduction Lipoprotein Transport Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis
Pathways
Drugs
Diseases
GWAS		Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		15 interacting genes: BLZF1 CCNA1 CCNB2 CDC37 CDK1 CDK3 CKS1B EEF1A1 GRB2 HSP90AA1 LDHB SSBP1 TSC22D4 UNC119 VTN	103 interacting genes: AAGAB ALDH2 AMOT ANKRD24 ANXA1 ANXA3 ANXA7 ARL15 ARL2 ARL3 ARL4D ASH2L BCR BRIX1 BTBD2 C16orf74 CBX8 CCL18 CD247 CD3E CD4 CDC42 CDKN1A CDKN2C CETN3 CKMT2 CKS2 COX17 CYB561D2 EIF2S2 ERH FKBPL FXYD6 FYN GIPC2 GSTM4 HCK HLA-DQA1 HMGB1 HSPB3 HSPE1 ID2 IL5RA ITSN1 KDM1A KRTAP1-3 KRTAP9-3 KRTAP9-8 LAMA4 LCK LIG4 LRIF1 LUC7L2 LYN MAP3K20 MAPK10 MAPK8IP2 MPHOSPH6 MRPS12 ORAI2 PAFAH1B3 PAPSS1 PCDHA4 PFN1 PHF10 PIN1 PLPP2 PPA1 PPP3CA PPP3CC PSMD11 PSMD2 PTPRS QTRT1 RAP1B RASSF6 RBPMS2 RCAN3 RCC1 RFC5 RGL2 RPA2 RPS6KA5 RUFY3 S100A4 S100A8 SAT1 SEPHS1 SERPINB9 SMN1 SULT1E1 TK1 TMEM200A TP53BP2 TP53I3 TP53INP1 TRDMT1 TSC22D1 UBE2B UBE2I UBQLN4 ZFP64 ZNF24
Entrez ID		1164	9094
HPRD ID		00300	04927
Ensembl ID		ENSG00000123975	ENSG00000109103
Uniprot IDs		P33552	K7EN86 Q13432
PDB IDs		1CKS 4Y72 4YC3 5HQ0 5LQF 6GU2 6GU3 6GU4 6GU6 6GU7	3GQQ 3RBQ 4GOJ 4GOK 5L7K 6H6A
Enriched GO Terms of Interacting Partners?
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