VASN and RNF31

Data Source:
BioGRID (two hybrid)

		VASN	RNF31
Description		vasorin	ring finger protein 31
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Lysosomal Membrane Plasma Membrane Cell Surface Integral Component Of Membrane Extracellular Matrix Extracellular Exosome	Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex LUBAC Complex
	Molecular Function	Protein Binding Cadherin Binding Transforming Growth Factor Beta Binding	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Ubiquitin Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Hypoxia Cellular Response To Redox State	Protein Polyubiquitination I-kappaB Kinase/NF-kappaB Signaling Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway CD40 Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Linear Polyubiquitination Positive Regulation Of Protein Targeting To Mitochondrion
Pathways			Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway
Drugs
Diseases
GWAS		Erectile dysfunction ( 30583798) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Suicide behavior ( 26079190)
Interacting Genes		53 interacting genes: ADAMTSL4 AQP3 CIB4 CYSRT1 GRN GUCD1 HOXA1 KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP4-1 KRTAP4-11 KRTAP4-2 KRTAP5-11 KRTAP6-3 KRTAP9-3 KRTAP9-8 LCE1C LCE2A LCE2C LCE2D LCE4A LNX1 MDFI MEOX2 MTUS2 NBPF19 NOTCH2NLA NR4A3 RGS17 RGS19 RGS20 RNF31 SMCP SSC4D TGFB1 TGFB2 TGFB3 TGM1 TRIP6 VWC2	46 interacting genes: ATN1 ATXN1 ATXN7 AZI2 CCDC24 CDC34 GFI1B HDAC6 KIF1A KRTAP9-2 NOS3 NR0B1 NR0B2 PITX1 PRKCA RBCK1 SEPTIN2 SMAD3 SNRPC SOCS3 SPATA2 STK4 TLE5 TRAF1 TRAF6 TRIM25 TSSC4 UBC UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2O UBE2Q1 UBE2Q2 UBE2R2 UBE2T UBE2W VASN VDAC1
Entrez ID		114990	55072
HPRD ID		10587	11516
Ensembl ID		ENSG00000168140	ENSG00000092098
Uniprot IDs		Q6EMK4	Q96EP0
PDB IDs			2CT7 4DBG 4JUY 4LJO 4LJP 4LJQ 4OWF 4OYJ 4OYK 4P09 4P0A 4P0B 5EDV 5LJN 5X0W 6GZY 6KC5 6KC6 6SC5 6SC6 6SC7 6SC8 6SC9
Enriched GO Terms of Interacting Partners?
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