TXNRD3 and SNAP29

Data Source:
BioGRID (two hybrid)

		TXNRD3	SNAP29
Description		thioredoxin reductase 3	synaptosome associated protein 29
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol	Golgi Membrane Autophagosome Membrane Nucleoplasm Cytoplasm Autophagosome Centrosome Cytosol Plasma Membrane Ciliary Pocket Membrane SNARE Complex Azurophil Granule Membrane Presynapse
	Molecular Function	Thioredoxin-disulfide Reductase Activity Protein Binding Protein Disulfide Oxidoreductase Activity Flavin Adenine Dinucleotide Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Multicellular Organism Development Spermatogenesis Cell Differentiation Cell Redox Homeostasis Cellular Oxidant Detoxification	Exocytosis Vesicle Targeting Vesicle Fusion Protein Transport Synaptic Vesicle Priming Autophagosome Membrane Docking Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Neutrophil Degranulation Cilium Assembly Membrane Fusion Autophagosome Maturation
Pathways			Neutrophil degranulation Intra-Golgi traffic
Drugs
Diseases			Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome; CEDNIK syndrome
GWAS
Interacting Genes		9 interacting genes: ANKRD36B BOLA1 BOLA2 BOLA2B CINP CTNNA3 FHL2 PACRGL SNAP29	34 interacting genes: AP2A1 ATF4 CD7 COG6 DNAJC5 EHD1 EHD3 FAM9B FAM9C ITSN2 KIFC3 LURAP1 NAPB NTAQ1 RASSF7 STX12 STX16 STX17 STX1A STX1B STX2 STX3 STX4 STX6 STX7 TRAF3 TSNARE1 TXNRD3 VAMP1 VAMP2 VAMP3 VAMP4 VAMP5 VAMP7
Entrez ID		114112	9342
HPRD ID			11968
Ensembl ID		ENSG00000197763	ENSG00000099940
Uniprot IDs		B4DRZ5 Q86VQ6	O95721
PDB IDs		3H8Q	4WY4 7BV6
Enriched GO Terms of Interacting Partners?
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