GABARAPL2 and ATG4B

Data Source:
BioGRID (enzymatic study, pull down, two hybrid)
HPRD (two hybrid)

		GABARAPL2	ATG4B
Description		GABA type A receptor associated protein like 2	autophagy related 4B cysteine peptidase
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GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Cytoplasm Autophagosome Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Cytoplasmic Vesicle	Cytosol
	Molecular Function	SNARE Binding Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding ATPase Binding	Endopeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Intra-Golgi Vesicle-mediated Transport Autophagy Cellular Response To Nitrogen Starvation Protein Transport Macroautophagy Positive Regulation Of ATPase Activity Protein Localization To Endoplasmic Reticulum Autophagosome Maturation Negative Regulation Of Proteasomal Protein Catabolic Process	Proteolysis Autophagy Protein Transport Macroautophagy Positive Regulation Of Protein Catabolic Process Protein Delipidation
Pathways		Macroautophagy TBC/RABGAPs	Macroautophagy
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Pancreatic cancer ( 25086665)	Asthma ( 31959851) Body mass index ( 29273807) Carotid intima media thickness ( 30510157) Crohn's disease ( 26192919) Prostate cancer ( 23535732)
Interacting Genes		89 interacting genes: AAMP AGTRAP AHNAK2 AMBRA1 ANK2 APP ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4D ATG7 BCL2L13 BNIP3L BSDC1 CALCOCO1 CALCOCO2 CLN8 CUL3 DYNLL1 DYNLL2 EGFR ERBB2 ERBB3 ERBB4 FUNDC1 GIMAP6 GOSR1 GPR37 HAP1 HSP90AB1 INSYN1 KASH5 KBTBD6 KBTBD7 KIAA1958 KIF16B KLHL5 KRTAP10-7 KRTAP10-9 LRSAM1 LZTR1 MAP1LC3B MCPH1 MEFV MLX NBR1 NEDD4 NPSR1 NSF NUDT15 OPTN OSBPL3 OSBPL7 PTPRA RAP1A RAP2A RB1CC1 RCN2 RETREG1 RETREG3 RPS2 SCYL3 SGTA SIK2 SMO SQSTM1 TAX1BP1 TBC1D25 TBC1D5 TBC1D9 TBC1D9B TEX264 TNIP1 TP53INP1 TP53INP2 TRIM21 TRIM32 TRIM45 TSR2 UBA5 ULK1 ULK2 VDR WDFY3 YWHAZ ZBTB2 ZNF774	6 interacting genes: GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MAP1LC3C
Entrez ID		11345	23192
HPRD ID		16246	16499
Ensembl ID		ENSG00000034713	ENSG00000168397
Uniprot IDs		P60520	B3KVU2 Q9Y4P1
PDB IDs		4CO7 6H8C	2CY7 2D1I 2Z0D 2Z0E 2ZZP 5LXH 5LXI
Enriched GO Terms of Interacting Partners?
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