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ECD and TXNIP
Data Source:
BioGRID
(affinity chromatography technology, pull down, two hybrid)
ECD
TXNIP
Description
ecdysoneless cell cycle regulator
thioredoxin interacting protein
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nucleus
Cytoplasm
Mitochondrial Intermembrane Space
Cytosol
Molecular Function
Protein Binding
Histone Acetyltransferase Binding
Enzyme Inhibitor Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Biological Process
MRNA Processing
RNA Splicing
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Transcription By RNA Polymerase II
Protein Import Into Nucleus
Cell Cycle
Response To Mechanical Stimulus
Response To Glucose
Protein Transport
Keratinocyte Differentiation
Response To Estradiol
Response To Progesterone
Regulation Of Cell Population Proliferation
Response To Drug
Response To Hydrogen Peroxide
Positive Regulation Of Apoptotic Process
Negative Regulation Of Catalytic Activity
Platelet-derived Growth Factor Receptor Signaling Pathway
Response To Calcium Ion
Negative Regulation Of Cell Division
Cellular Response To Tumor Cell
Pathways
The NLRP3 inflammasome
The NLRP3 inflammasome
Regulation of FOXO transcriptional activity by acetylation
Purinergic signaling in leishmaniasis infection
Purinergic signaling in leishmaniasis infection
Drugs
Diseases
GWAS
Interacting Genes
6 interacting genes:
CSNK2A1
EWSR1
NR3C1
PSEN2
TET2
TXNIP
20 interacting genes:
DDIT4
ECD
FHL1
HDAC1
HDAC3
HSPB2
ITCH
KPNA2
MAPK1
NLGN3
PRKAA1
PTPN11
SCEL
SMURF2
TRAF6
TXN
TXNRD1
UBR5
ZBTB16
ZBTB32
Entrez ID
11319
10628
HPRD ID
11032
05964
Ensembl ID
ENSG00000122882
ENSG00000265972
Uniprot IDs
O95905
Q9H3M7
PDB IDs
4GEI
4GEJ
4GFX
4LL1
4LL4
4ROF
4ROJ
5CQ2
5DF6
5DWS
5DZD
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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