VPS45 and STX16

Data Source:
HPRD (two hybrid, in vitro)

		VPS45	STX16
Description		vacuolar protein sorting 45 homolog	syntaxin 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cellular_component Golgi Apparatus Endosome Membrane Integral Component Of Membrane	Golgi Membrane Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Focal Adhesion Endomembrane System Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane SNARE Complex Golgi Cisterna Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Molecular_function Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Blood Coagulation Vesicle-mediated Transport	Intracellular Protein Transport Vesicle Fusion Retrograde Transport, Endosome To Golgi Vesicle Docking Golgi Ribbon Formation
Pathways		Intra-Golgi traffic Factors involved in megakaryocyte development and platelet production	Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases			Pseudohypoparathyroidism
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Broad depression or schizophrenia ( 30626913) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Obesity in adult survivors of childhood cancer not exposed to cranial radiation ( 25963547) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Uric acid levels ( 21294900)	Cardiovascular risk factors (age interaction) ( 20838585) Hemoglobin ( 32888494)
Interacting Genes		11 interacting genes: BCAR3 CASP8 IGF1R PAX2 PTPN1 RB1CC1 RBSN SNTG1 STX16 VPS11 VPS18	14 interacting genes: MEOX2 NAPB PTPN12 RHOU SNAP29 STX1A STX2 STX4 STX6 VAMP3 VAMP4 VAMP5 VPS45 VTI1A
Entrez ID		11311	8675
HPRD ID		10301	04718
Ensembl ID		ENSG00000136631	ENSG00000124222
Uniprot IDs		A0A2R8YE10 B7Z360 B7Z5D4 Q9NRW7	B4DJX9 O14662
PDB IDs
Enriched GO Terms of Interacting Partners?
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