MRAP2 and ISLR2

Data Source:
BioGRID (two hybrid)

		MRAP2	ISLR2
Description		melanocortin 2 receptor accessory protein 2	immunoglobulin superfamily containing leucine rich repeat 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane	Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Protein Binding Receptor Regulator Activity Corticotropin Hormone Receptor Binding Type 3 Melanocortin Receptor Binding Type 4 Melanocortin Receptor Binding Type 5 Melanocortin Receptor Binding Identical Protein Binding Type 1 Melanocortin Receptor Binding	Protein Binding
	Biological Process	Energy Reserve Metabolic Process Feeding Behavior Protein Localization To Plasma Membrane Energy Homeostasis Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Protein Localization To Plasma Membrane	Positive Regulation Of Axon Extension
Pathways
Drugs
Diseases
GWAS		Schizophrenia ( 28991256) Whole brain grey matter density ( 31530798)	Blood protein levels ( 30072576 29875488)
Interacting Genes		6 interacting genes: APH1A APP ISLR2 MC2R SGTA TMEM80	6 interacting genes: EMP1 LAPTM4B MRAP2 NKG7 STRIT1 UPK1B
Entrez ID		112609	57611
HPRD ID		12843	13865
Ensembl ID		ENSG00000135324	ENSG00000167178
Uniprot IDs		Q96G30	Q6UXK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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