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DUSP10 and KRTAP3-2
Data Source:
BioGRID
(two hybrid)
DUSP10
KRTAP3-2
Description
dual specificity phosphatase 10
keratin associated protein 3-2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Nuclear Speck
Cytosol
Keratin Filament
Molecular Function
Phosphoprotein Phosphatase Activity
Protein Tyrosine Phosphatase Activity
Protein Binding
Protein Tyrosine/threonine Phosphatase Activity
JUN Kinase Binding
Phosphatase Activity
MAP Kinase Tyrosine/serine/threonine Phosphatase Activity
MAP Kinase Phosphatase Activity
Mitogen-activated Protein Kinase P38 Binding
Mitogen-activated Protein Kinase Binding
Protein Serine Phosphatase Activity
Protein Threonine Phosphatase Activity
Structural Molecule Activity
Protein Binding
Biological Process
Inactivation Of MAPK Activity
Regulation Of Adaptive Immune Response
Protein Dephosphorylation
Negative Regulation Of Epithelial Cell Migration
Dephosphorylation
Negative Regulation Of Cell Migration
Response To Lipopolysaccharide
Peptidyl-tyrosine Dephosphorylation
Peptidyl-threonine Dephosphorylation
Negative Regulation Of JUN Kinase Activity
Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation
Positive Regulation Of Regulatory T Cell Differentiation
Negative Regulation Of JNK Cascade
Oligodendrocyte Differentiation
Negative Regulation Of Oligodendrocyte Differentiation
Negative Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Respiratory Burst Involved In Inflammatory Response
Negative Regulation Of ERK1 And ERK2 Cascade
Regulation Of Brown Fat Cell Differentiation
Negative Regulation Of P38MAPK Cascade
Negative Regulation Of Epithelium Regeneration
Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity
Keratinization
Pathways
RAF-independent MAPK1/3 activation
Negative regulation of MAPK pathway
Signaling by MAPK mutants
Keratinization
Drugs
Diseases
GWAS
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
Colorectal cancer (
25990418
20972440
24836286
29471430
)
Colorectal cancer or advanced adenoma (
30510241
)
Copper levels (
26025379
)
Lung function (FEV1) (
30061609
)
Lung function (FVC) (
30061609
)
Progressive supranuclear palsy (
30089514
)
Serum thyroid-stimulating hormone levels (
25436638
)
Tonsillectomy (
27182965
28928442
)
White matter lesion progression (
26451028
)
White matter lesion progression (adjusted for white matter lesion burden at baseline) (
26451028
)
Interacting Genes
20 interacting genes:
CMTM6
ERBB4
FHL2
FN1
FNDC3B
HOXA1
HTT
IGF1R
KRTAP3-2
MAPK10
MAPK11
MAPK14
MAPK3
MAPK8
MAPK9
PTK7
ROR2
RPS11
SLX1B
SNX2
75 interacting genes:
ADAM12
ADAMTSL3
AQP1
ARFGAP1
ATG9A
C5orf60
CATSPER1
CCDC28A-AS1
CELF5
CERK
CNNM3
COL8A1
CREB5
DHRS1
DUSP10
EFEMP2
FAM71C
FOXD2
FRS3
GAD1
GATA1
GUCD1
HOXA1
HOXB9
HYAL2
HYPK
ITGB5
KIF25-AS1
KPRP
KRTAP10-1
KRTAP10-5
KRTAP10-8
KRTAP12-1
KRTAP12-2
KRTAP13-3
KRTAP15-1
KRTAP26-1
KRTAP4-12
KRTAP4-4
KRTAP9-2
KRTAP9-3
LASP1
LCE1A
LCE1B
LCE1F
LCE2A
LCE3A
LCE3C
LCE3D
LCE3E
LCE4A
MAN2B2
MAPKBP1
NR1D2
NTM
NUFIP2
OLIG3
OTX1
PCSK5
PLSCR3
POGZ
POU4F2
PPP1R32
PRR34
R3HDM2
SLC13A5
SMARCC1
SPRY1
TBC1D16
TRIM42
TRIP13
VASN
YIPF3
ZIC1
ZIM2
Entrez ID
11221
83897
HPRD ID
12320
13938
Ensembl ID
ENSG00000143507
ENSG00000212900
Uniprot IDs
Q9Y6W6
Q9BYR7
PDB IDs
1ZZW
2OUC
2OUD
3TG1
6MC1
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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