RPP14 and CAPZB

Data Source:
BioGRID (two hybrid)

		RPP14	CAPZB
Description		ribonuclease P/MRP subunit p14	capping actin protein of muscle Z-line subunit beta
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex	Cytosol Cytoskeleton F-actin Capping Protein Complex Actin Cytoskeleton Sarcomere Extracellular Exosome WASH Complex
	Molecular Function	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	Actin Binding Protein Binding Cadherin Binding Actin Filament Binding
	Biological Process	TRNA 5'-leader Removal RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Cell Morphogenesis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cytoskeleton Organization Blood Coagulation Regulation Of Lamellipodium Assembly Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Cell Morphogenesis Actin Cytoskeleton Organization Barbed-end Actin Filament Capping Negative Regulation Of Filopodium Assembly
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol	MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Height ( 28552196) Hemoglobin levels ( 32327693) Platelet distribution width ( 32888494) Refractive error ( 32231278) Rheumatoid arthritis (ACPA-positive) ( 24532676) Total cholesterol levels ( 30275531)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease and psoriasis ( 22482804) Heel bone mineral density ( 30598549) Height ( 28552196) Hyperthyroidism ( 30367059) Hypothyroidism ( 30367059 27182965) Lead levels in blood ( 25820613) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Serum thyroid-stimulating hormone levels ( 24852370) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997 25743335) Thyroid volume ( 21565293)
Interacting Genes		22 interacting genes: A2M ACTN2 ATP5F1B CAPZB DOCK7 EXOSC8 GEMIN2 IGSF21 KMT2B LIMD1 MSH2 NOVA1 PKM POP4 POP5 PSME1 RPP25 RPP30 RPP38 RPP40 WIZ ZNF277	9 interacting genes: BCCIP CDC42 HSPA8 MRPL20 MTPN PTN RPP14 SIRPA VHL
Entrez ID		11102	832
HPRD ID		18001	11872
Ensembl ID		ENSG00000163684	ENSG00000077549
Uniprot IDs		O95059	A0A384MR50 B1AK85 B1AK88 B4DWA6 P47756 Q7L4N0
PDB IDs		6AHR 6AHU
Enriched GO Terms of Interacting Partners?
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