RCC1 and CHGB

Data Source:
BioGRID (two hybrid)

		RCC1	CHGB
Description		regulator of chromosome condensation 1	chromogranin B
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Cytoplasm Nuclear Membrane Protein-containing Complex	Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule
	Molecular Function	Chromatin Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding Nucleosome Binding Nucleosomal DNA Binding Histone Binding Sulfate Binding Protein Heterodimerization Activity	Hormone Activity Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Regulation Of Mitotic Nuclear Division Viral Process Ran Protein Signal Transduction Regulation Of Catalytic Activity Spindle Assembly Cell Division Regulation Of Mitotic Spindle Assembly	Signal Transduction Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Rev-mediated nuclear export of HIV RNA Nuclear import of Rev protein Postmitotic nuclear pore complex (NPC) reformation	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917) Systolic blood pressure ( 30578418)	Metabolite levels ( 23823483) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		50 interacting genes: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 ERCC6 FAF1 FBXO7 FLAD1 GNB2 H2AC18 H2AC20 H2BC21 H3C1 HADHB HMGA1 HOXD8 KMT2B KPNA3 KPNA4 LRIF1 NGFR NTMT1 NUDT21 NUP98 PDHB PKM PTMA RAN RANBP1 RANBP3 RPA1 SDF4 SPRED1 SUMO2 TLE1 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135	34 interacting genes: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 LRRK1 LRRK2 MARK3 MFHAS1 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PRAG1 PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SLC25A6 TAZ TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1
Entrez ID		1104	1114
HPRD ID		01559	07512
Ensembl ID		ENSG00000180198	ENSG00000089199
Uniprot IDs		A0A0S2Z3I4 A0A0S2Z404 P18754 Q5T081	P05060
PDB IDs		1A12 1I2M 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 5TBK 6DUB
Enriched GO Terms of Interacting Partners?
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