STIP1 and PTGES3

Data Source:
BioGRID (biochemical)
HPRD (in vitro)

		STIP1	PTGES3
Description		stress induced phosphoprotein 1	prostaglandin E synthase 3
Image
GO Annotations	Cellular Component	Nucleus Golgi Apparatus Cytosol Protein-containing Complex Chaperone Complex	Chromosome, Telomeric Region Nucleus Nucleoplasm Telomerase Holoenzyme Complex Cytosol Protein-containing Complex Chaperone Complex
	Molecular Function	RNA Binding Protein Binding Protein C-terminus Binding Hsp70 Protein Binding Chaperone Binding Hsp90 Protein Binding	Telomerase Activity Protein Binding Prostaglandin-E Synthase Activity Unfolded Protein Binding Chaperone Binding Hsp90 Protein Binding DNA Polymerase Binding
	Biological Process	Cellular Response To Interleukin-7	Telomere Maintenance Prostaglandin Biosynthetic Process Protein Folding Xenobiotic Metabolic Process Telomere Maintenance Via Telomerase Signal Transduction Cyclooxygenase Pathway Positive Regulation Of Phosphorylation Protein Stabilization Chaperone Cofactor-dependent Protein Refolding Chaperone-mediated Protein Complex Assembly Positive Regulation Of Telomerase Activity Regulation Of Cellular Response To Heat Telomerase Holoenzyme Complex Assembly
Pathways		HSP90 chaperone cycle for steroid hormone receptors (SHR)	Synthesis of Prostaglandins (PG) and Thromboxanes (TX) HSP90 chaperone cycle for steroid hormone receptors (SHR) HSF1 activation Attenuation phase Aryl hydrocarbon receptor signalling ESR-mediated signaling Estrogen-dependent gene expression Potential therapeutics for SARS
Drugs		Copper	Acetaminophen Grn163l Copper
Diseases
GWAS		Attention deficit hyperactivity disorder ( 21784300) Crohn's disease ( 28067908) Fruit consumption ( 32066663)	Asthma ( 31619474) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 27863252) Mean platelet volume ( 22139419) Platelet count ( 22139419) Reticulocyte count ( 32888494)
Interacting Genes		23 interacting genes: ACD ACVR1 AIP APP CDC37 CLCN1 CLK1 EGFR ERBB2 FKBP4 FKBP5 HSP90AA1 HSPA14 HSPA1A HSPA1B HSPA8 LMO2 MAP3K8 POT1 PRNP PTGES3 SUMO2 SUMO4	29 interacting genes: AHR AHSA1 AIP ARNT CASP3 CASP7 CAV3 CD2AP CDC37 COPG1 COPG2 DNAJB1 DNMT3A EIF2AK2 ERBB3 ESR1 FES GZMB HSF1 HSP90AA1 HSP90AB1 HSPA1A HSPB1 NR3C1 NR3C2 STIP1 SURF1 TERT THRA
Entrez ID		10963	10728
HPRD ID		05454	06138
Ensembl ID		ENSG00000168439	ENSG00000110958
Uniprot IDs		P31948 V9HW72	A0A024RB32 A0A087WYT3 B3KUY2 Q15185
PDB IDs		1ELR 1ELW 2LNI 2NC9 3ESK 3FWV	1EJF 1LG0
Enriched GO Terms of Interacting Partners?
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