OS9 and CPNE6

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		OS9	CPNE6
Description		OS9 endoplasmic reticulum lectin	copine 6
Image			No pdb structure
GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum Quality Control Compartment	Endosome Plasma Membrane Membrane Axon Dendrite Perikaryon Synapse Clathrin-coated Endocytic Vesicle Extracellular Exosome
	Molecular Function	Protease Binding Protein Binding Carbohydrate Binding	Phosphatidylserine Binding Transporter Activity Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Targeting Protein Retention In ER Lumen Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Response To Endoplasmic Reticulum Stress Transmembrane Transport Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Endoplasmic Reticulum Mannose Trimming	Lipid Metabolic Process Chemical Synaptic Transmission Nervous System Development Vesicle-mediated Transport Cell Differentiation Glycerophospholipid Biosynthetic Process Cellular Response To Calcium Ion Positive Regulation Of Dendrite Extension
Pathways		ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)	Glycerophospholipid biosynthesis
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Multiple sclerosis ( 31604244) Rheumatoid arthritis (ACPA-positive) ( 24532676)	Triglyceride levels ( 32203549)
Interacting Genes		19 interacting genes: ACVR1B CPNE6 CREB3 DCSTAMP DYSF EGLN1 EGLN3 EIF6 FOXM1 HIF1A HSP90B1 LINC00839 MEP1B RBX1 SMAD2 SNRPD2 SREBF2 TRPV4 ZNF512B	14 interacting genes: AGR2 AK5 ANXA7 CDKN1A GRB7 LAMTOR3 MAPK11 MEOX2 NOTCH3 OS9 PIN1 SMN1 TK1 TTR
Entrez ID		10956	9362
HPRD ID		17804	05748
Ensembl ID		ENSG00000135506	ENSG00000100884
Uniprot IDs		Q13438	B3KWK1 O95741
PDB IDs		3AIH
Enriched GO Terms of Interacting Partners?
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