CBX1 and DCAF7

Data Source:
BioGRID (affinity chromatography technology)

		CBX1	DCAF7
Description		chromobox 1	DDB1 and CUL4 associated factor 7
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromosome, Telomeric Region Chromatin Heterochromatin Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Pericentric Heterochromatin Spindle Chromocenter Site Of DNA Damage	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Body Protein-containing Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Chromatin Binding Protein Binding Enzyme Binding Identical Protein Binding Histone Methyltransferase Binding	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated	Multicellular Organism Development Protein Ubiquitination Post-translational Protein Modification
Pathways		HCMV Early Events	Association of TriC/CCT with target proteins during biosynthesis Neddylation
Drugs
Diseases
GWAS		Body mass index ( 26426971 20935630) Generalized epilepsy ( 22949513)
Interacting Genes		36 interacting genes: ABI3BP ARL5A ATXN7L2 BAHD1 BARD1 BRCA1 CBX3 CBX5 CHAF1A DNMT1 DNMT3A DNMT3B EMSY H1-4 H3-4 H3C1 H3C3 HECW2 HSPB1 KLF11 LNX1 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TRIM24 TRIM28 UCHL1 VHL VTN ZNF280C	7 interacting genes: APP ATP13A2 BMPR1B DYRK1B LIG1 PWP2 YWHAG
Entrez ID		10951	10238
HPRD ID		05149	09340
Ensembl ID		ENSG00000108468	ENSG00000136485
Uniprot IDs		P83916 Q6IBN6	P61962
PDB IDs		2FMM 3F2U 3Q6S 5T1G 6D07 6D08
Enriched GO Terms of Interacting Partners?
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