MORF4L1 and ARID3A

Data Source:
BioGRID (two hybrid)

		MORF4L1	ARID3A
Description		mortality factor 4 like 1	AT-rich interaction domain 3A
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Sin3 Complex Nuclear Speck NuA4 Histone Acetyltransferase Complex	Nucleus Nucleoplasm Cytosol Membrane Raft
	Molecular Function	Protein Binding Protein N-terminus Binding	DNA Binding Chromatin Binding Transcription Coregulator Activity Protein Binding Identical Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Chromatin Silencing Histone Acetylation Histone Deacetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation	Regulation Of Transcription By RNA Polymerase II DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Positive Regulation Of Transcription By RNA Polymerase II
Pathways		HATs acetylate histones	TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Drugs
Diseases
GWAS		Coronary artery disease ( 32469254 30104761 33020668) Coronary heart disease ( 21378988) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Pulse pressure ( 27841878 30578418) Refractive error ( 32231278) Squamous cell lung carcinoma ( 28604730)	High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494 27863252) Primary biliary cholangitis ( 28425483) Systemic lupus erythematosus ( 28714469) Vertical cup-disc ratio ( 20548946)
Interacting Genes		76 interacting genes: APP ARID3A ARRDC3 BEND7 BEX5 CALM1 CAMK2B CEP57L1 CWC27 DMAP1 DRAP1 DYSF EP300 FAM13C FAM9B FBXO16 FHL3 FXR2 GMCL1 GOLGA2 GOLGA6A GSC2 H3-4 HINFP HMBOX1 IKZF1 KPNA2 L3MBTL3 LHX2 LMNA LZTS2 MEOX1 MEOX2 MRFAP1 MRFAP1L1 MRGBP MRPL12 MSL1 NAB2 NAV2 NECAB1 NKD1 NMI PBXIP1 PHF12 PIBF1 PICK1 PLEKHA3 PSMC1 RACGAP1 RB1 RCBTB2 REL SH3GLB2 SYN3 TEPSIN TEX11 TFCP2 THAP1 TLE5 TNIP1 TNNT1 TNNT2 TRIM41 TULP3 UBP1 VPS26A ZBTB10 ZBTB26 ZBTB43 ZBTB8B ZBTB9 ZC3H7A ZNF276 ZNF438 ZNF449	21 interacting genes: ANKRD11 APP BTK DSP E2F1 E2F2 E2F4 KRT31 MAGEB2 MAGEB4 MORF4L1 MORF4L2 NOTCH2NLA PML REP15 SP100 TIMM8A TP53 TTC32 UBE2E3 XPA
Entrez ID		10933	1820
HPRD ID		09532	10343
Ensembl ID		ENSG00000185787	ENSG00000116017
Uniprot IDs		Q9UBU8	Q99856
PDB IDs		2AQL 2EFI 2F5J 2F5K 2LKM 2N1D 6AGO 6INE	2KK0 4LJX
Enriched GO Terms of Interacting Partners?
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