CEACAM8 and CEACAM6

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		CEACAM8	CEACAM6
Description		CEA cell adhesion molecule 8	CEA cell adhesion molecule 6
Image
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Cell Surface Anchored Component Of Membrane Azurophil Granule Membrane Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane	Extracellular Space Plasma Membrane Cell Surface Apical Plasma Membrane Anchored Component Of Membrane Azurophil Granule Membrane
	Molecular Function	Protein Binding Protein Heterodimerization Activity	Protein Binding Identical Protein Binding Protein Heterodimerization Activity
	Biological Process	Immune Response Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Neutrophil Degranulation Leukocyte Migration	Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Positive Regulation Of Heterotypic Cell-cell Adhesion Neutrophil Degranulation Leukocyte Migration Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Negative Regulation Of Anoikis
Pathways		Fibronectin matrix formation Cell surface interactions at the vascular wall Neutrophil degranulation	Fibronectin matrix formation Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs
Diseases
GWAS			Serum carcinoembryonic antigen levels ( 31666285)
Interacting Genes		2 interacting genes: CEACAM1 CEACAM6	32 interacting genes: APP ASPG CARTPT CEACAM1 CEACAM5 CEACAM7 CEACAM8 CIB1 CSTF2 EXOC3L1 FOXH1 GCM2 GPANK1 HGS HPCAL4 KANK2 MSS51 MYOZ1 PITX1 POM121 QRICH1 RHOXF2 SHC3 SMARCD1 TLX3 TNXB UBQLN2 VENTX VEZF1 WWOX ZMYND19 ZNF76
Entrez ID		1088	4680
HPRD ID		07630	01233
Ensembl ID		ENSG00000124469	ENSG00000086548
Uniprot IDs		B4DLI3 P31997 Q0Z7S6	P40199
PDB IDs		2DKS 4WTZ 4Y88 4YIQ	4WHC 4WTZ 4Y8A 4YIQ
Enriched GO Terms of Interacting Partners?
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