POLR1G and NCL

Data Source:
BioGRID (pull down)

		POLR1G	NCL
Description		RNA polymerase I subunit G	nucleolin
Image		No pdb structure
GO Annotations	Cellular Component	RNA Polymerase I Transcription Regulator Complex Fibrillar Center Nucleoplasm Chromosome Nucleolus RNA Polymerase I Complex Mitochondrion Cytosol	Nucleus Nucleoplasm Spliceosomal Complex Chromosome Nucleolus Cell Cortex Membrane Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	RNA Binding DNA-directed 5'-3' RNA Polymerase Activity	RNA Binding Protein Binding Protein C-terminus Binding Telomeric DNA Binding Identical Protein Binding DNA Topoisomerase Binding MRNA 5'-UTR Binding
	Biological Process	Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway RRNA Transcription Positive Regulation Of Gene Expression, Epigenetic	Angiogenesis Negative Regulation Of Translation Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 23728934) Common carotid intima-media thickness in HIV negative individuals ( 29206233) Eating disorders (purging via substances) ( 23568457) Height ( 31562340) Noise-induced hearing loss ( 26121033)
Interacting Genes		8 interacting genes: CD3E NCL NFKBIB POLR1C POLR1D POLR1E TAF1A UBTF	57 interacting genes: ADAP1 ADAP2 CD3E CDK1 CDKN2A CLK1 CSNK2A1 CSNK2A2 DUX4 ERG ESR1 ETS1 FMR1 GRB2 GZF1 GZMA H1-2 H2AC20 H2AX H2BC21 H3-4 HMGA1 IL7R LINC01554 MDC1 MDK MDM2 MYB MYBL1 NBN NDRG1 NPM1 NR3C1 PARP1 POLR1G PPARGC1A PPM1D PRKCZ PRMT5 PTGS1 RAD51 S100A11 SREK1 SRPK2 SSB STAU1 SUMO2 TERF2 TERT TOP1 TP53 VHL XRCC6 YWHAQ ZFP36 ZFP41 ZNF689
Entrez ID		10849	4691
HPRD ID		00125	01245
Ensembl ID		ENSG00000117877	ENSG00000115053
Uniprot IDs		O15446	B3KM80 P19338
PDB IDs			2FC8 2FC9 2KRR
Enriched GO Terms of Interacting Partners?
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