HSPH1 and PGK1

Data Source:
HPRD (in vitro)

		HSPH1	PGK1
Description		heat shock protein family H (Hsp110) member 1	phosphoglycerate kinase 1
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GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Protein-containing Complex Extracellular Exosome Endocytic Vesicle Lumen	Extracellular Space Cytosol Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Binding ATP Binding Alpha-tubulin Binding	Phosphoglycerate Kinase Activity Protein Binding ATP Binding ADP Binding Protein-disulfide Reductase Activity
	Biological Process	Receptor-mediated Endocytosis Response To Unfolded Protein Positive Regulation Of MHC Class I Biosynthetic Process Regulation Of Catalytic Activity Chaperone Cofactor-dependent Protein Refolding Positive Regulation Of NK T Cell Activation Regulation Of Cellular Response To Heat	Gluconeogenesis Glycolytic Process Phosphorylation Negative Regulation Of Angiogenesis Epithelial Cell Differentiation Plasminogen Activation Canonical Glycolysis Cellular Response To Hypoxia
Pathways		Scavenging by Class F Receptors Scavenging by Class F Receptors Regulation of HSF1-mediated heat shock response	Glycolysis Gluconeogenesis Manipulation of host energy metabolism
Drugs		Phenethyl Isothiocyanate	Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate 3-phospho-D-glyceric acid Copper Artenimol
Diseases			Anemia due to disorders of glycolytic enzymes, including: Hexokinase (HK) deficiency; Phosphoglycerate kinase 1 (PGK1) deficiency; Triose-phosphate isomerase (TPI) deficiency; Glucose phosphate isomerase (GPI) deficiency; Bisphosphoglycerate mutase (BPGM) deficiency
GWAS		Metabolite levels ( 23823483)	Mean platelet volume ( 32888494)
Interacting Genes		16 interacting genes: ADD1 CFL1 CHD3 CSNK2A1 CSNK2A2 DYNLRB1 HSPA8 NMI PAFAH1B1 PAFAH1B3 PGK1 PTEN STK39 TUBA4A UBA1 VAV2	14 interacting genes: BECN1 CDC7 CSNK2A1 DISC1 GAPDH HIF1A HSPH1 LINC01554 NAA10 PCNA RHOU SUMO2 SUMO4 YWHAQ
Entrez ID		10808	5230
HPRD ID		09990	02412
Ensembl ID		ENSG00000120694	ENSG00000102144
Uniprot IDs		A0A024RDQ0 A0A024RDS1 A0A0A0MSM0 B4DY72 Q92598	P00558 V9HWF4
PDB IDs		6GFA	2WZB 2WZC 2WZD 2X13 2X14 2X15 2XE6 2XE7 2XE8 2Y3I 2YBE 2ZGV 3C39 3C3A 3C3B 3C3C 3ZOZ 4AXX 4O33 5M1R 5M3U 5M6Z 5MXM 5NP8 5O7D
Enriched GO Terms of Interacting Partners?
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