IGF2BP3 and MIRLET7G

Data Source:
BioGRID (unspecified method)

		IGF2BP3	MIRLET7G
Description		insulin like growth factor 2 mRNA binding protein 3	microRNA let-7g
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Extracellular Space
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Translation Regulator Activity MRNA 5'-UTR Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Regulation Of Cytokine Production Translation Nervous System Development Anatomical Structure Morphogenesis Regulation Of Gene Expression Negative Regulation Of Translation Regulation Of MRNA Stability MRNA Transport Regulation Of RNA Metabolic Process	Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Gene Silencing By MiRNA Positive Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cellular Response To Glucose Stimulus Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Pathways		Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA
Drugs
Diseases
GWAS		Birth weight ( 31043758 27680694) Height ( 28552196 20881960 25282103 23563607) Hip circumference adjusted for BMI ( 25673412) Infant length ( 25281659) Offspring birth weight ( 31043758) Personality dimensions ( 23903073) Type 2 diabetes ( 30297969) White blood cell count ( 32888494)	Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 23974872)
Interacting Genes		76 interacting genes: DUX4 MEOX2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PCBP1 PIH1D2	116 interacting genes: ADARB1 APOBEC3B AQR ATXN2L C1QBP CCAR1 CDC40 CDC5L CELF1 CHERP CPSF1 CRTAP CSTF3 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 EPRS1 ESRP1 FAM98A FAM98B FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PAXBP1 PDCD11 PLOD1 PLRG1 PTBP1 PTCD3 PUF60 PUM1 PUM2 PURA PURB QARS1 RARS1 RBFOX2 RBM10 RBM12B RBM14 RBM17 RBM4 RBM4B RBM5 RBM6 RBMS1 RTCA RTCB SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SF3B5 SFPQ SPOUT1 STRBP SUGP1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 XAB2 YBX1 YBX2 YBX3 ZFR
Entrez ID		10643	406890
HPRD ID		16306
Ensembl ID		ENSG00000136231	ENSG00000199150
Uniprot IDs		O00425
PDB IDs		2E44 6FQ1 6FQR 6GQE 6GX6
Enriched GO Terms of Interacting Partners?
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