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TBL3 and AURKB
Data Source:
HPRD
(two hybrid)
TBL3
AURKB
Description
transducin beta like 3
aurora kinase B
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Nucleolus
90S Preribosome
Small-subunit Processome
Kinetochore
Condensed Chromosome, Centromeric Region
Nucleus
Nucleoplasm
Spindle
Cytosol
Spindle Microtubule
Chromocenter
Midbody
Spindle Pole Centrosome
Chromosome Passenger Complex
Spindle Midzone
Mitotic Spindle Pole
Mitotic Spindle Midzone
Molecular Function
RNA Binding
Protein Binding
U3 SnoRNA Binding
Protein Serine/threonine Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Kinase Binding
Histone Serine Kinase Activity
Metal Ion Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Endonucleolytic Cleavage To Generate Mature 5'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
RRNA Processing
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of B Cell Apoptotic Process
Protein Phosphorylation
Ubiquitin-dependent Protein Catabolic Process
Spindle Organization
Mitotic Spindle Organization
Mitotic Spindle Assembly Checkpoint
Aging
Cell Population Proliferation
Attachment Of Spindle Microtubules To Kinetochore
Abscission
Histone Modification
Anaphase-promoting Complex-dependent Catabolic Process
Negative Regulation Of Protein Binding
Positive Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Cytokinesis
Negative Regulation Of Cytokinesis
Positive Regulation Of Cytokinesis
Protein Localization To Kinetochore
Cellular Response To UV
Cleavage Furrow Formation
Histone H3-S28 Phosphorylation
Mitotic Cytokinesis Checkpoint
Protein Autophosphorylation
Mitotic Spindle Midzone Assembly
Positive Regulation Of Telomerase Activity
Regulation Of Chromosome Segregation
Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Telomere Capping
Positive Regulation Of Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore
Pathways
rRNA modification in the nucleus and cytosol
Major pathway of rRNA processing in the nucleolus and cytosol
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA replication proteins
RHO GTPases Activate Formins
Regulation of TP53 Activity through Phosphorylation
Mitotic Prometaphase
Regulation of MECP2 expression and activity
EML4 and NUDC in mitotic spindle formation
Drugs
Hesperidin
AT9283
Enzastaurin
Reversine
Fostamatinib
Diseases
GWAS
Anxiety disorders (
31906708
)
Apolipoprotein A1 levels (
32203549
)
Interacting Genes
11 interacting genes:
AHR
APPBP2
AURKB
CACNB4
CUL4B
DHX30
ITSN2
NR2E3
SFN
URM1
USP11
52 interacting genes:
AJUBA
ANKZF1
APP
BCL2L11
BIRC5
CBX3
CDCA8
CENPA
CIB1
CYLD
DCUN1D1
DES
EVI5
FBXL2
FLOT1
GFAP
H3-4
H3C1
H3C14
HASPIN
INCENP
KLHL13
KLHL21
KLHL9
LATS1
LATS2
LNX1
LRRK2
MAPRE1
MAPRE2
MAPRE3
MFHAS1
NCAPH
NDC80
NINL
NSUN2
NUF2
PKM
PSMA3
PTPA
RACGAP1
RACK1
RAD52
RASA1
RASSF1
SEPTIN1
SKA1
SKA3
TACC1
TBL3
TGFBR1
UBE2I
Entrez ID
10607
9212
HPRD ID
09327
05397
Ensembl ID
ENSG00000183751
ENSG00000178999
Uniprot IDs
Q12788
Q96GD4
PDB IDs
4AF3
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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