USP16 and FBXO11

Data Source:
BioGRID (unspecified method)

		USP16	FBXO11
Description		ubiquitin specific peptidase 16	F-box protein 11
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Ubiquitin Ligase Complex Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol
	Molecular Function	Transcription Coactivator Activity Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Zinc Ion Binding Histone Binding Ubiquitin Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein-arginine N-methyltransferase Activity
	Biological Process	Mitotic Cell Cycle Regulation Of Transcription By RNA Polymerase II Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Histone Deubiquitination Protein Deubiquitination Protein Phosphopantetheinylation Monoubiquitinated Histone H2A Deubiquitination Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Translational Elongation Positive Regulation Of Transcription By RNA Polymerase II Protein Homotetramerization Cell Division Regulation Of Cell Cycle Histone H2A K63-linked Deubiquitination Mitotic Nuclear Division	Protein Polyubiquitination Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Sensory Perception Of Sound Protein Ubiquitination Peptidyl-arginine N-methylation Regulation Of Apoptotic Process Post-translational Protein Modification
Pathways		Ub-specific processing proteases	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Asthma ( 27611488) Chronotype ( 30696823) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Macular thickness ( 30535121) PR interval ( 32439900) Refractive error ( 32231278) Schizophrenia ( 23894747)
Interacting Genes		15 interacting genes: CALM1 CDK1 EXOSC10 FBXO11 H2AC18 H2AC20 H2AC4 H2AZ1 H2BC3 H4-16 PLK1 PTOV1 TTK UBC UBD	5 interacting genes: BCL6 HDAC6 SKP1 TP53 USP16
Entrez ID		10600	80204
HPRD ID		06881	06985
Ensembl ID		ENSG00000156256	ENSG00000138081
Uniprot IDs		Q9Y5T5	Q86XK2
PDB IDs		2I50	5VMD
Enriched GO Terms of Interacting Partners?
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