CEBPB and SMARCC1

Data Source:
HPRD (in vivo)

		CEBPB	SMARCC1
Description		CCAAT enhancer binding protein beta	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
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GO Annotations	Cellular Component	Condensed Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix CHOP-C/EBP Complex	Chromatin XY Body Nucleus Nucleoplasm Cytoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Kinase Binding Histone Acetyltransferase Binding Glucocorticoid Receptor Binding Protein Homodimerization Activity Histone Deacetylase Binding Ubiquitin-like Protein Ligase Binding Protein Heterodimerization Activity Sequence-specific Double-stranded DNA Binding	Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding Protein N-terminus Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Ovarian Follicle Development Embryonic Placenta Development Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Acute-phase Response Inflammatory Response Immune Response Memory Neuron Differentiation Regulation Of Interleukin-6 Production Positive Regulation Of Interleukin-4 Production Mammary Gland Epithelial Cell Proliferation Response To Endoplasmic Reticulum Stress Negative Regulation Of T Cell Proliferation Defense Response To Bacterium Negative Regulation Of Neuron Apoptotic Process Regulation Of Cell Differentiation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Osteoblast Differentiation Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Inflammatory Response Brown Fat Cell Differentiation Mammary Gland Epithelial Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Positive Regulation Of Biomineral Tissue Development Cellular Response To Lipopolysaccharide Cellular Response To Amino Acid Stimulus Cellular Response To Interleukin-1 Cellular Response To Organic Cyclic Compound Hepatocyte Proliferation Liver Regeneration Positive Regulation Of Cold-induced Thermogenesis Regulation Of Odontoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Positive Regulation Of Sodium-dependent Phosphate Transport Regulation Of Dendritic Cell Differentiation	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Insulin Receptor Signaling Pathway Animal Organ Morphogenesis Prostate Gland Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Senescence-Associated Secretory Phenotype (SASP) Senescence-Associated Secretory Phenotype (SASP) ATF4 activates genes in response to endoplasmic reticulum stress Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation Transcriptional Regulation by VENTX Transcriptional regulation of granulopoiesis Response of EIF2AK4 (GCN2) to amino acid deficiency Response of EIF2AK4 (GCN2) to amino acid deficiency Response of EIF2AK1 (HRI) to heme deficiency Response of EIF2AK1 (HRI) to heme deficiency	RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs		Quercetin
Diseases
GWAS		Bronchodilator response in asthma ( 25562107) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 23128233) Meconium ileus in cystic fibrosis ( 30807572) Type 2 diabetes ( 30297969 32499647 30718926)	Household income (MTAG) ( 31844048) Renal underexcretion gout ( 32238385) Systolic blood pressure ( 31928498)
Interacting Genes		57 interacting genes: AR ATF2 ATF4 CAMK2A CCL3 CCNT1 CDK9 CEBPA CEBPD CEBPG CREB1 CREBBP DDIT3 EGFR EGR1 ELK1 EP300 ESR1 FOXO1 HMGA1 HMGB1 HNRNPK HOMER3 HSF1 KAT2A KAT2B MAPK1 MAPK3 MED23 MYB MYC NCOR2 NFKB1 NOLC1 NR3C1 PTGES2 RARB RB1 RELA RPS6KA1 RPS6KA5 RUNX1 RUNX2 SMAD3 SMAD4 SMARCA4 SMARCB1 SMARCC1 SP1 SPI1 SPIB SRF STAT5A STAT6 TAF9 TRIB1 TRIM28	53 interacting genes: ADAMTSL4 ADD1 AKT1 CCNE1 CEBPB CFP CIDEB CYSRT1 EWSR1 FANCA FUS GATA1 GLRX3 GSTO2 ITCH KLF1 KRTAP13-3 KRTAP19-2 KRTAP21-2 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 LRP2BP MGAT5B MSL1 MYC NCOA1 NEDD4 NONO NR3C1 OTX1 PLSCR1 PPIP5K2 PRMT5 PTH1R RELB SIN3A SLC15A2 SMARCA4 SMARCD3 SP1 SPATA12 TAF15 TRIM42 UFSP1 VGLL3 ZNF581
Entrez ID		1051	6599
HPRD ID		01801	03435
Ensembl ID		ENSG00000172216	ENSG00000173473
Uniprot IDs		P17676	Q58EY4 Q92922
PDB IDs		1GTW 1GU4 1GU5 1H88 1H89 1H8A 1HJB 1IO4 2E42 2E43 6MG1 6MG2 6MG3	2YUS 5GJK 6KZ7
Enriched GO Terms of Interacting Partners?
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