TADA3 and USP5

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		TADA3	USP5
Description		transcriptional adaptor 3	ubiquitin specific peptidase 5
Image		No pdb structure
GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex STAGA Complex Transcription Factor TFTC Complex Mitotic Spindle	Nucleus Lysosome Cytosol
	Molecular Function	Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Nuclear Receptor Binding Protein Domain Specific Binding Nuclear Receptor Coactivator Activity	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Ubiquitin Binding
	Biological Process	Mitotic Cell Cycle Regulation Of Protein Phosphorylation Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Protein Deubiquitination Intracellular Estrogen Receptor Signaling Pathway Regulation Of Histone Deacetylation Regulation Of Protein Stability Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Transcription, DNA-templated Regulation Of Tubulin Deacetylation	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Deubiquitination Protein Phosphopantetheinylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Deubiquitination
Pathways		HATs acetylate histones Ub-specific processing proteases	Ub-specific processing proteases Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		32 interacting genes: ADPGK ANKRD12 ANKRD36B AR CCNC EIF3J EP300 ESR1 FAM107B H3-4 HEXIM2 HSPA8 ING5 KDM1A MAGEH1 MFHAS1 NR1I2 PIAS4 RARA RFX1 RXRA RXRB SAP18 SGF29 STX11 TADA2A TP53 TXLNB TXNRD2 USP5 XRCC6 ZNF7	26 interacting genes: APP DAZAP2 DVL2 PJA1 PLA2G2A RFFL RNF11 RNF216 SMURF1 SPART STK33 SUMO2 TADA3 TMEM239 TRIM26 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIM8 TRIML1 UBC UBE2S UBTD2 USP28
Entrez ID		10474	8078
HPRD ID		04252	03265
Ensembl ID		ENSG00000171148	ENSG00000111667
Uniprot IDs		A0A024R2D7 A8K899 O75528	A0A140VJZ1 P45974
PDB IDs			2DAG 2DAK 2G43 2G45 3IHP 6DXH 6DXT 6NFT 6P9G
Enriched GO Terms of Interacting Partners?
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