Description |
vav guanine nucleotide exchange factor 3 |
insulin like growth factor 1 receptor |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065)
- Asthma and hay fever ( 24388013)
- Autoimmune thyroid disease ( 32581359)
- Bipolar disorder ( 31043756)
- Differentiated thyroid cancer ( 28703219)
- Eosinophil percentage of white cells ( 32888494)
- Hashimoto thyroiditis versus Graves' disease ( 25429627)
- Hip circumference adjusted for BMI ( 28552196)
- Hypothyroidism ( 30367059 27182965 22493691)
- IgA nephropathy ( 25305756)
- Medication use (thyroid preparations) ( 31015401)
- Night sleep phenotypes ( 27126917)
- Papillary thyroid cancer ( 28703219)
- Plasma thyroid-stimulating hormone levels ( 24722205)
- Refractive error ( 32231278)
- Response to antiepileptic mood-stabilizing treatment in bipolar disorder ( 32627186)
- Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
- Thyroid stimulating hormone levels ( 32769997)
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Interacting Genes |
25 interacting genes:
AR
CBLB
EGFR
ERBB2
ERBB3
ERBB4
ESR1
GAB1
GRB2
IGF1R
INSR
KIT
LCP2
MET
PIK3R1
PLCG1
RAC1
RHOA
RHOG
RINT1
ROS1
SH3BP2
SHC1
ZRANB1
ZYX
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95 interacting genes:
AMY2A
APP
ARHGEF12
BAP1
CAV1
CBL
CDK4
CDKN2B
CRK
CRKL
CSK
CYP17A1
DOK4
DOK5
DUSP10
DUSP14
DUSP15
DUSP18
DUSP19
DUSP21
DUSP26
DUSP29
EEA1
EHD1
ERBB2
ESR1
FFAR2
FGFR4
GIPC1
GNAI1
GNAI2
GRB10
GRB14
GRM1
HOXC6
IGF1
IGF2
IGFBP3
IL13RA2
ILKAP
INS
INSR
IRS1
IRS2
IRS4
ITGB1
JAK1
JAK2
KCNIP3
KDELR2
KL
KLK5
KRT27
LYPD3
MAP3K5
MDM2
MTA3
NAT2
NEDD4
NF2
PCNA
PIK3R1
PIK3R2
PIK3R3
PPM1A
PRKCD
PRKD1
PTPN1
PTPN11
PTPN12
PTPN6
PTPN7
PTPRR
RACK1
RASA1
RELA
RPL11
SH2B1
SHC1
SIRPA
SOCS1
SOCS2
SOCS3
SRC
STAT3
STYX
THRSP
TTYH2
UBC
VAV3
VPS45
YWHAB
YWHAE
YWHAG
YWHAZ
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Entrez ID |
10451 |
3480 |
HPRD ID |
05706 |
00932 |
Ensembl ID |
ENSG00000134215
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ENSG00000140443
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Uniprot IDs |
Q9UKW4
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C9J5X1
P08069
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PDB IDs |
2D86
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1IGR
1JQH
1K3A
1M7N
1P4O
2OJ9
2ZM3
3D94
3F5P
3I81
3LVP
3LW0
3NW5
3NW6
3NW7
3O23
3QQU
4D2R
4XSS
5FXQ
5FXR
5FXS
5HZN
5U8Q
5U8R
6JK8
6VWG
6VWH
6VWI
6VWJ
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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