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CDX2 and DNMT3L
Data Source:
BioGRID
(pull down)
CDX2
DNMT3L
Description
caudal type homeobox 2
DNA methyltransferase 3 like
Image
GO Annotations
Cellular Component
Chromatin
Condensed Nuclear Chromosome
Nucleus
Nucleoplasm
Transcription Repressor Complex
Nucleus
Cytosol
ESC/E(Z) Complex
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Methyl-CpG Binding
Sequence-specific Double-stranded DNA Binding
Protein Binding
Enzyme Activator Activity
Enzyme Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Blood Vessel Development
Trophectodermal Cell Differentiation
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Cell Population Proliferation
Endosome To Lysosome Transport
Embryo Development
Animal Organ Morphogenesis
Anterior/posterior Axis Specification
Regulation Of Somitogenesis
Cell Differentiation
Somatic Stem Cell Population Maintenance
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Positive Regulation Of Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Intestinal Epithelial Cell Differentiation
Labyrinthine Layer Development
DNA Methylation
Regulation Of Gene Expression By Genetic Imprinting
Male Meiosis I
Spermatogenesis
DNA Methylation On Cytosine
DNA Methylation Involved In Gamete Generation
Negative Regulation Of Transcription, DNA-templated
Stem Cell Differentiation
Regulation Of Catalytic Activity
Negative Regulation Of DNA Methylation
Positive Regulation Of DNA Methylation
Pathways
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
DNA methylation
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Monocyte count (
27863252
)
Pancreatic cancer (
25086665
)
Interacting Genes
16 interacting genes:
ACAT2
CDK2
CFAP206
CREBBP
DNMT3L
EP300
GSK3B
HNF1A
KRTAP4-12
MAPK1
MAPK14
PAX6
SMARCA4
SMARCB1
SMARCD1
UBB
78 interacting genes:
-
ASH2L
ATF1
ATF2
ATF3
ATF4
BLZF1
CDX2
CREB1
CREBL2
CREM
DDIT3
DLX4
DMTF1
DNMT3A
DNMT3B
DR1
E2F3
E2F5
E2F6
EGR1
EGR2
EGR4
ESR1
ESR2
ETS1
F2RL1
FOS
FOSB
FOSL1
FOSL2
GATA1
GMEB1
GSK3B
GTF2H2
GTF2I
GTF3C5
H2AC20
H2BC21
H3C14
H4C14
HAND1
HAND2
HDAC1
HNF4G
HOXA5
HOXC11
ID1
JUN
JUNB
KLF12
LDB1
LHX2
MAFK
MECP2
MED7
MEF2A
MEF2D
NFIL3
NFKB1
NR1H2
NR1I2
NR1I3
NR2E1
NR3C1
NR6A1
NUDT21
PDZD4
PHPT1
RELA
RSL24D1
RXRA
SMAD1
SMAD3
SMAD4
TLE5
TP53
YY1
Entrez ID
1045
29947
HPRD ID
02622
09417
Ensembl ID
ENSG00000165556
ENSG00000142182
Uniprot IDs
Q99626
Q9UJW3
PDB IDs
5LTY
6ES2
6ES3
2PV0
2PVC
2QRV
4U7P
4U7T
5YX2
6BRR
6F57
6KDA
6KDB
6KDL
6KDP
6KDT
6U8P
6U8V
6U8W
6U8X
6U90
6U91
6W89
6W8B
6W8D
6W8J
Enriched GO Terms of Interacting Partners
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