Wiki-Pi
About
Search
Browse
People
Updates
Search
CALCOCO2 and PRKAA2
Data Source:
BioGRID
(two hybrid)
CALCOCO2
PRKAA2
Description
calcium binding and coiled-coil domain 2
protein kinase AMP-activated catalytic subunit alpha 2
Image
GO Annotations
Cellular Component
Autophagosome Membrane
Nucleus
Cytoplasm
Autophagosome
Cytosol
Cytoskeleton
Membrane
PML Body
Cytoplasmic Vesicle
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Cytoplasmic Stress Granule
Nuclear Speck
Axon
Dendrite
Neuronal Cell Body
Molecular Function
Protein Binding
Protein Homodimerization Activity
Metal Ion Binding
Chromatin Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
AMP-activated Protein Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Histone Serine Kinase Activity
Metal Ion Binding
[hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity
[acetyl-CoA Carboxylase] Kinase Activity
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Viral Process
Response To Interferon-gamma
Xenophagy
Positive Regulation Of Autophagosome Maturation
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Cholesterol Biosynthetic Process
Carnitine Shuttle
Cell Cycle Arrest
Signal Transduction
Lipid Biosynthetic Process
Positive Regulation Of Autophagy
Negative Regulation Of Gene Expression
Response To Muscle Activity
Wnt Signaling Pathway
Macroautophagy
Positive Regulation Of Macroautophagy
Regulation Of Macroautophagy
Cellular Response To Nutrient Levels
Negative Regulation Of TOR Signaling
Cellular Response To Oxidative Stress
Histone-serine Phosphorylation
Intracellular Signal Transduction
Cellular Response To Drug
Cellular Response To Glucose Starvation
Regulation Of Fatty Acid Biosynthetic Process
Glucose Homeostasis
Regulation Of Circadian Rhythm
Negative Regulation Of Apoptotic Process
Positive Regulation Of Glycolytic Process
Rhythmic Process
Fatty Acid Homeostasis
Regulation Of Stress Granule Assembly
Regulation Of Microtubule Cytoskeleton Organization
Cellular Response To Calcium Ion
Cellular Response To Glucose Stimulus
Cellular Response To Prostaglandin E Stimulus
Energy Homeostasis
Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Cellular Protein Localization
Negative Regulation Of Tubulin Deacetylation
Positive Regulation Of Peptidyl-lysine Acetylation
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Macroautophagy
AMPK inhibits chREBP transcriptional activation activity
AMPK inhibits chREBP transcriptional activation activity
Carnitine metabolism
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of TP53 Activity through Phosphorylation
Lipophagy
Activation of AMPK downstream of NMDARs
Drugs
Adenosine phosphate
Acetylsalicylic acid
Fostamatinib
Diseases
GWAS
Blood protein levels (
30072576
)
Chronotype (
30696823
)
Type 2 diabetes (
29358691
29632382
)
Type 2 diabetes (adjusted for BMI) (
29632382
)
Lymphocyte counts (
22286170
)
Interacting Genes
180 interacting genes:
ABLIM1
ADSL
AKAP17A
AMMECR1
AP5B1
APEX2
ARHGEF39
ARHGEF5
ARNT2
ATG5
AXIN1
BAHD1
BCL6B
BEX2
CBX8
CCDC120
CCDC185
CCDC33
CCNH
CDC7
CELA2B
CEP57L1
CHCHD3
CNNM3
CPNE7
CWF19L2
DAXX
DAZAP2
DBNDD2
DCTN4
DCX
DDIT4L
DDX6
DOCK2
DUSP12
DUSP26
EEF1E1
EFHC1
ELOA2
ENKD1
EXOSC5
FAM107A
FAM161A
FAM168A
FAM189A2
FAM214B
FAM90A1
FARS2
FASTK
FBF1
FBXL18
FKBPL
FNDC11
FOXD4L3
FXR2
GABARAPL1
GABARAPL2
GATAD2B
GCA
GEMIN4
GIT2
GLYCTK
HDAC4
HDAC7
HLX
HNRNPLL
HOXB5
HOXB9
IKBKG
IL16
IQUB
KANSL1
KAT7
KLHL35
KLHL42
LENG1
LGALS8
LIMS2
LITAF
LMF2
LMO2
LMO4
LNX1
LONRF1
LSM4
MAGOHB
MAP1LC3C
MCM10
METTL17
MID2
MOS
MTPAP
MVP
MXI1
MYH6
MYO6
NAA10
NDN
NFU1
ORC5
PCGF1
PEF1
PEG10
PFDN5
PHF1
PIAS4
PLEKHN1
POLI
POLR2A
PPP1R18
PRKAA2
PRKAB2
PRPF18
PRPF31
PSMA1
PSME4
PTBP1
PTBP2
QARS1
RAB35
RABL6
RBM15
RHPN1
RIN1
RNF11
RPA2
RPL9
RPS27A
RTN4IP1
RTP5
RXRB
SCAND1
SCNM1
SDCBP
SETD5
SHC1
SLC15A3
SMARCD1
SMCP
SNRPB
SPATA24
SRI
STAMBPL1
STK16
TACO1
TBC1D22B
TBK1
TBKBP1
TBRG4
TCL1A
TEKT3
TENT2
TLE5
TP53RK
TRAF2
TRAF4
TRAF6
TSGA10IP
TTC23L
UBAC2
USP2
VARS1
VPS72
ZBTB4
ZC2HC1C
ZNF101
ZNF205
ZNF337
ZNF408
ZNF414
ZNF426
ZNF451
ZNF564
ZNF581
ZNF638
ZNF648
ZNF688
ZNF696
ZNF774
ZNF80
122 interacting genes:
ABI1
ABI2
ACACA
ACACB
AIMP2
AKAP8L
AMOT
AMOTL2
ANAPC11
APPBP2
ARRDC3
AVPI1
C19orf47
CALCOCO1
CALCOCO2
CCDC172
CCDC33
CCNB1IP1
CDC42EP1
CDR2
CDX4
CPSF7
CTAG2
CYSRT1
DNAAF6
DNM2
DNMT1
DVL3
EEF2K
EMILIN1
EPM2A
EPN2
FNDC3B
FOS
GIGYF1
GLI1
GOLGA2
GOLGA6A
GRAP2
HAT1
HMBOX1
HNF4A
HOMEZ
IKZF1
IKZF3
KCTD1
KCTD9
KIAA1328
KIF16B
KIF24
KIFC3
KRT16
KRT31
KRTAP1-3
KRTAP10-3
KRTAP10-9
L3MBTL3
LCN2
LEP
LZTS2
MKRN3
MORN3
MRFAP1
MTUS2
MYCL
MYOZ1
NAB2
NECAB2
NONO
NOTCH2NLA
NRAP
NRBF2
NUTM1
PBXIP1
PFKFB2
PLEKHN1
PPP1R32
PRDM6
PRKAB1
PRKAG1
PRKAR1B
PRKN
PRPH
RASAL3
RBBP7
RBPMS
REL
RFX6
RPTOR
SERTAD3
SKIV2L
SLA2
SNW1
SOHLH1
SPRY1
STAC2
STK11
TCF4
TFAP2A
TIFA
TLE5
TMOD1
TRIP13
TRIP6
TSC22D4
UBE2I
USH1C
USH1G
USHBP1
USP10
VPS28
VPS37B
VPS52
WASHC1
WWP1
WWP2
YPEL3
ZBTB8A
ZMYND12
ZNF212
ZNF397
ZSCAN23
Entrez ID
10241
5563
HPRD ID
06846
02735
Ensembl ID
ENSG00000136436
ENSG00000162409
Uniprot IDs
Q13137
P54646
PDB IDs
2MXP
3VVV
3VVW
4GXL
4HAN
4XKL
5AAQ
5Z7A
5Z7L
2H6D
2LTU
2YZA
3AQV
4CFE
4CFF
4ZHX
5EZV
5ISO
6B1U
6B2E
6BX6
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?