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HDAC5 and DDX20
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vitro, in vivo)
HDAC5
DDX20
Description
histone deacetylase 5
DEAD-box helicase 20
Image
GO Annotations
Cellular Component
Histone Deacetylase Complex
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Nuclear Speck
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cytoskeleton
Membrane
SMN Complex
SMN-Sm Protein Complex
Gemini Of Coiled Bodies
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Factor Binding
Chromatin Binding
Histone Deacetylase Activity
Protein Kinase C Binding
Protein Binding
Transcription Factor Binding
NAD-dependent Histone Deacetylase Activity (H3-K14 Specific)
Protein Deacetylase Activity
Identical Protein Binding
Histone Deacetylase Binding
Metal Ion Binding
Repressing Transcription Factor Binding
DNA Binding
RNA Binding
RNA Helicase Activity
Protein Binding
ATP Binding
Repressing Transcription Factor Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Chromatin Remodeling
Chromatin Silencing
Protein Deacetylation
Inflammatory Response
Regulation Of Myotube Differentiation
Negative Regulation Of Myotube Differentiation
Response To Activity
Histone Deacetylation
Neuron Differentiation
B Cell Differentiation
Cellular Response To Insulin Stimulus
Regulation Of Gene Expression, Epigenetic
B Cell Activation
Response To Cocaine
Response To Drug
Regulation Of Protein Binding
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of DNA-binding Transcription Factor Activity
Histone H3 Deacetylation
Cellular Response To Lipopolysaccharide
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Regulation Of Histone H3-K9 Acetylation
Negative Regulation Of Transcription By RNA Polymerase II
Spliceosomal Tri-snRNP Complex Assembly
Spliceosomal SnRNP Assembly
RNA Processing
Positive Regulation Of Apoptotic Process
Import Into Nucleus
Pathways
NOTCH1 Intracellular Domain Regulates Transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
Notch-HLH transcription pathway
Regulation of PTEN gene transcription
snRNP Assembly
Drugs
Belinostat
Panobinostat
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
Bipolar disorder (
31043756
)
Bone mineral density (hip) (
19801982
)
Bone mineral density (spine) (
19801982
)
HDL cholesterol levels (
32203549
)
Heel bone mineral density (
30598549
28869591
)
Mean platelet volume (
32888494
)
Body mass index (
29273807
)
Metabolite levels (
23823483
)
Venous thromboembolism (
32232851
)
Interacting Genes
61 interacting genes:
ANKRA2
ANKRD11
ATF3
BCL6
BCOR
BRMS1
CAMK1
CAMTA2
CBX5
CIITA
CTBP1
DDX20
DYRK1B
EEF1G
ESR1
GABARAP
GATA1
GATA2
GCM1
GNB1
H3C1
HDAC3
HDAC7
HIF1A
HOXC11
HR
JDP2
KLF4
LMO2
MAFF
MEF2A
MEF2C
MEF2D
NCOR1
NCOR2
NFATC1
NFKB2
NFKBIE
NRIP1
PHB2
PKN1
PKN2
PRKAA1
PRKCD
PRKD1
RFXANK
RUNX3
SFN
SIK1
SIK2
SIK3
SLC2A4RG
SMAD3
SUV39H1
TAB2
UBC
UBE2I
YWHAB
YWHAE
YWHAQ
ZBTB16
32 interacting genes:
AGO2
APP
CRYAB
DHX9
ETV3
GEMIN2
GEMIN4
GEMIN5
HDAC2
HDAC5
NCOR1
NCOR2
NR0B2
NUFIP1
PRRC2A
RN7SL1
RNU1-1
RNU2-1
SIN3A
SMN1
SMN2
SNRPB
SNRPD1
SNRPD2
SNRPD3
SNRPE
SNRPF
SNRPG
SNUPN
STXBP2
STXBP3
TP53
Entrez ID
10014
11218
HPRD ID
09246
05859
Ensembl ID
ENSG00000108840
ENSG00000064703
Uniprot IDs
Q9UQL6
Q9H4N4
Q9UHI6
PDB IDs
5UWI
2OXC
3B7G
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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