SYCE1L and ATF5

Data Source:
BioGRID (two hybrid)

		SYCE1L	ATF5
Description		synaptonemal complex central element protein 1 like	activating transcription factor 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Intermediate Filament Cytoskeleton	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Centrosome Cytosol
	Molecular Function		Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Tubulin Binding Kinase Binding Sequence-specific DNA Binding
	Biological Process	Synaptonemal Complex Assembly	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Circadian Rhythm Negative Regulation Of Cell Population Proliferation Post-embryonic Development Olfactory Bulb Interneuron Development Cerebellar Granule Cell Precursor Proliferation Multicellular Organism Growth Negative Regulation Of Apoptotic Process Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Centrosome Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition
Pathways			Response of EIF2AK1 (HRI) to heme deficiency
Drugs			Pseudoephedrine
Diseases
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		36 interacting genes: ALDH18A1 ANKRD36 ATF5 BFSP2 BOLL C1orf216 C22orf39 CALN1 CCDC146 CCDC196 CCHCR1 CENPP CST1 CYTH4 DPPA3 EPC1 FGA HSF2BP KCNIP2 KIAA1328 LCA5L LNX1 MED10 NOL4 NTAQ1 ODF1 OIP5 PFDN5 SCHIP1 SLC7A8 SMARCD1 SPHKAP SRSF10 TNNI1 TRAPPC13 ZNF526	17 interacting genes: ATXN1 CCDC6 CCND3 CDC34 CEBPA CEBPE CEBPG DISC1 EIF2B1 EP300 FBXO7 GABBR1 GABBR2 GIT2 GPS2 SYCE1L TTR
Entrez ID		100130958	22809
HPRD ID			05906
Ensembl ID		ENSG00000205078	ENSG00000169136
Uniprot IDs		A8MT33	A0A024QZG3 Q9Y2D1
PDB IDs
Enriched GO Terms of Interacting Partners?
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