ZBTB33 and GYS1

Data Source:
BioGRID (two hybrid)

		ZBTB33	GYS1
Description		zinc finger and BTB domain containing 33	glycogen synthase 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane	Cytoplasm Cytosol Membrane Inclusion Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Methyl-CpG Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Glycogen (starch) Synthase Activity Protein Binding Glucose Binding Protein Kinase Binding Glycogen Synthase Activity, Transferring Glucose-1-phosphate
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Wnt Signaling Pathway Intracellular Signal Transduction Negative Regulation Of Transcription, DNA-templated	Glycogen Biosynthetic Process Heart Development
Pathways			Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1)
Drugs
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS
Interacting Genes		9 interacting genes: CBFA2T3 CTNND1 GSDMD GYS1 NCOR1 NUDT22 SUMO2 SUMO3 TRIML2	43 interacting genes: AIMP2 APP BEND7 CCDC33 CDCA8 CLVS2 CRX CSNK2A1 EFHC2 FAM228A GSK3B GYG1 GYG2 HOXB6 HOXC8 IHO1 INCA1 KATNBL1 KLF1 KLF4 MAPKAPK5 MEOX1 NDUFB7 NHLRC1 PCYT1A PINX1 PLAGL2 PNMA5 PRKACA RBM48 SNIP1 SORBS3 SUMO2 TFAP2D TLE5 WASHC1 ZBTB33 ZNF212 ZNF326 ZNF474 ZNF552 ZNF620 ZNF774
Entrez ID		10009	2997
HPRD ID		02269	00721
Ensembl ID		ENSG00000177485	ENSG00000104812
Uniprot IDs		Q86T24	P13807
PDB IDs		2LT7 3FKC 3M4T 3M8V 4F6M 4F6N 5VMU 5VMV 5VMW 5VMX 5VMY 5VMZ 6DF5 6DF8 6DF9 6DFA 6DFB 6DFC 6V8U
Enriched GO Terms of Interacting Partners?
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