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BMP15

Description bone morphogenetic protein 15
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Space
  • Endoplasmic Reticulum Lumen
Molecular Function
  • Cytokine Activity
  • Growth Factor Activity
  • Type I Activin Receptor Binding
Biological Process
  • Ovarian Follicle Development
  • Female Gamete Generation
  • Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
  • BMP Signaling Pathway
  • Post-translational Protein Modification
  • Cellular Protein Metabolic Process
  • Positive Regulation Of Transcription, DNA-templated
  • Granulosa Cell Development
  • SMAD Protein Signal Transduction
Pathways
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • Post-translational protein phosphorylation
Drugs
Diseases
  • Premature ovarian failure
  • 46,XX disorders of sex development (Disorders of gonadal development), including: Ovotesticular DSD; Testicular DSD; Ovarian dysgenesis
GWAS
Novel Interacting Genes 1 novel interacting genes: KDM6A
Interacting Genes 2 interacting genes: BMPR1B GDF9
Entrez ID 9210
HPRD ID 02216
Ensembl ID ENSG00000130385
Uniprot IDs O95972
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025