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SLC6A3
Description
solute carrier family 6 member 3
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Surface
Integral Component Of Membrane
Flotillin Complex
Axon
Neuronal Cell Body Membrane
Presynaptic Membrane
Neuron Projection
Neuronal Cell Body
Membrane Raft
Dopaminergic Synapse
Integral Component Of Postsynaptic Membrane
Integral Component Of Presynaptic Membrane
Molecular Function
Protease Binding
Signaling Receptor Binding
Neurotransmitter Transmembrane Transporter Activity
Dopamine:sodium Symporter Activity
Norepinephrine:sodium Symporter Activity
Protein Binding
Drug Binding
Monoamine Transmembrane Transporter Activity
Dopamine Binding
Protein-containing Complex Binding
Metal Ion Binding
Protein N-terminus Binding
Protein Phosphatase 2A Binding
Biological Process
Neurotransmitter Transport
Aging
Lactation
Sensory Perception Of Smell
Locomotory Behavior
Response To Iron Ion
Monoamine Transport
Dopamine Transport
Norepinephrine Transport
Adenohypophysis Development
Response To Nicotine
Sodium Ion Transmembrane Transport
Positive Regulation Of Multicellular Organism Growth
Regulation Of Dopamine Metabolic Process
Neurotransmitter Biosynthetic Process
Response To Cocaine
Dopamine Biosynthetic Process
Dopamine Catabolic Process
Response To Drug
Response To Ethanol
Dopamine Uptake Involved In Synaptic Transmission
Response To CAMP
Norepinephrine Uptake
Prepulse Inhibition
Dopamine Uptake
Hyaloid Vascular Plexus Regression
Pathways
Dopamine clearance from the synaptic cleft
Na+/Cl- dependent neurotransmitter transporters
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS)
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS)
Drugs
Amphetamine
Phentermine
Benzatropine
Venlafaxine
Loxapine
Methylphenidate
Meperidine
Imipramine
Duloxetine
Amoxapine
Mazindol
Procaine
Trimipramine
Modafinil
Phenmetrazine
Pseudoephedrine
Benzphetamine
Cocaine
Diethylpropion
Dopamine
Sertraline
Sibutramine
Chlorpheniramine
Diphenylpyraline
Nefazodone
Bupropion
Chloroprocaine
Escitalopram
Aripiprazole
Ephedra sinica root
MMDA
Midomafetamine
Fencamfamin
4-Methoxyamphetamine
Dextroamphetamine
Metamfetamine
Vanoxerine
Nomifensine
Altropane
Mianserin
Tesofensine
Trodusquemine
Armodafinil
Desvenlafaxine
Dexmethylphenidate
Dasotraline
Solriamfetol
Diseases
GWAS
Pancreatic cancer (
25086665
)
Novel Interacting Genes
2 novel interacting genes:
AHRR
MRPL36
Interacting Genes
9 interacting genes:
DRD2
MTNR1A
NEDD4
PICK1
RACK1
SNCA
SNTA1
STX1A
TGFB1I1
Entrez ID
6531
HPRD ID
00543
Ensembl ID
ENSG00000142319
Uniprot IDs
Q01959
PDB IDs
Enriched GO Terms of Interacting Partners
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