IDO1

Description		indoleamine 2,3-dioxygenase 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Smooth Muscle Contractile Fiber Stereocilium Bundle
	Molecular Function	Tryptophan 2,3-dioxygenase Activity Electron Transfer Activity Heme Binding Indoleamine 2,3-dioxygenase Activity Metal Ion Binding
	Biological Process	Immune System Process Positive Regulation Of T Cell Tolerance Induction Positive Regulation Of Chronic Inflammatory Response Positive Regulation Of Type 2 Immune Response Tryptophan Catabolic Process Inflammatory Response Female Pregnancy Tryptophan Catabolic Process To Kynurenine Electron Transport Chain Response To Lipopolysaccharide Negative Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-12 Production Multicellular Organismal Response To Stress Kynurenic Acid Biosynthetic Process 'de Novo' NAD Biosynthetic Process From Tryptophan Swimming Behavior Negative Regulation Of T Cell Proliferation Regulation Of Activated T Cell Proliferation Negative Regulation Of T Cell Apoptotic Process Positive Regulation Of T Cell Apoptotic Process
Pathways		Tryptophan catabolism
Drugs		Nitric Oxide Cannabidiol Medical Cannabis Nabiximols
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood protein levels ( 29875488)
Novel Interacting Genes		6 novel interacting genes: ADRB3 DCTN6 DUSP4 RBPMS SFRP1 SLC20A2
Interacting Genes		5 interacting genes: APP DDX24 FBXL17 PPP1R16A TERF2IP
Entrez ID		3620
HPRD ID		00935
Ensembl ID		ENSG00000131203
Uniprot IDs		A0A348GSI3 P14902
PDB IDs		2D0T 2D0U 4PK5 4PK6 4U72 4U74 5EK2 5EK3 5EK4 5ETW 5WHR 5WMU 5WMV 5WMW 5WMX 5WN8 5XE1 6AZU 6AZV 6AZW 6CXU 6CXV 6DPQ 6DPR 6E35 6E40 6E41 6E42 6E43 6E44 6E45 6E46 6F0A 6KOF 6KPS 6KW7 6MQ6 6O3I 6PU7 6PZ1 6R63 6TUE 6V52 6WJY
Enriched GO Terms of Interacting Partners?
Tagcloud ?