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JCHAIN

Description joining chain of multimeric IgA and IgM
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Extracellular Exosome
  • Monomeric IgA Immunoglobulin Complex
  • Dimeric IgA Immunoglobulin Complex
  • Secretory IgA Immunoglobulin Complex
  • Secretory Dimeric IgA Immunoglobulin Complex
  • Pentameric IgM Immunoglobulin Complex
  • Hexameric IgM Immunoglobulin Complex
  • Blood Microparticle
Molecular Function
  • Single-stranded DNA Binding
  • Antigen Binding
  • IgA Binding
  • Protein-macromolecule Adaptor Activity
  • Phosphatidylcholine Binding
  • Immunoglobulin Receptor Binding
  • Protein Homodimerization Activity
  • Peptidoglycan Binding
Biological Process
  • Retina Homeostasis
  • Adaptive Immune Response
  • Glomerular Filtration
  • Receptor-mediated Endocytosis
  • Immune Response
  • Humoral Immune Response
  • Antibacterial Humoral Response
  • Innate Immune Response
  • Leukocyte Migration
  • Positive Regulation Of Respiratory Burst
  • Protein-containing Complex Assembly
Pathways
  • Cell surface interactions at the vascular wall
  • Scavenging of heme from plasma
Drugs
  • Zinc
  • Zinc acetate
  • Zinc chloride
  • Zinc sulfate, unspecified form
Diseases
GWAS
Interacting Genes 2 interacting genes: CD79A IGHM
Entrez ID 3512
HPRD ID 00991
Ensembl ID ENSG00000132465
Uniprot IDs P01591
PDB IDs 6KXS 6LX3 6LXW 6UE7 6UE8 6UE9 6UEA
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025