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IGFBP1
Description
insulin like growth factor binding protein 1
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Endoplasmic Reticulum Lumen
Golgi Apparatus
Molecular Function
Signaling Receptor Binding
Protein Binding
Insulin-like Growth Factor Binding
Insulin-like Growth Factor I Binding
Insulin-like Growth Factor II Binding
Biological Process
Signal Transduction
Aging
Insulin Receptor Signaling Pathway
Positive Regulation Of Cell Growth
PERK-mediated Unfolded Protein Response
Tissue Regeneration
Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Post-translational Protein Modification
Cellular Protein Metabolic Process
Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways
ATF4 activates genes in response to endoplasmic reticulum stress
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Drugs
Diseases
GWAS
Major depressive disorder (
23377640
)
Night sleep phenotypes (
27126917
)
Offspring birth weight (
31043758
)
Poor prognosis in Crohn's disease (
28067912
)
Pulse pressure (
28135244
30487518
)
Rheumatoid arthritis (
21156761
)
Subjective response to lithium treatment in bipolar disorder (
26503763
)
Systolic blood pressure (
27618447
)
Interacting Genes
4 interacting genes:
IGF1
IGF2
MMP26
TF
Entrez ID
3484
HPRD ID
00897
Ensembl ID
ENSG00000146678
Uniprot IDs
P08833
PDB IDs
1ZT3
1ZT5
2DSQ
Enriched GO Terms of Interacting Partners
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Tagcloud
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