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FBXL5

Description F-box and leucine rich repeat protein 5
Image
GO Annotations Cellular Component
  • Ubiquitin Ligase Complex
  • Cytosol
  • SCF Ubiquitin Ligase Complex
  • Perinuclear Region Of Cytoplasm
Molecular Function
  • Ubiquitin-protein Transferase Activity
  • Iron Ion Binding
  • Protein Binding
Biological Process
  • Protein Polyubiquitination
  • Cellular Iron Ion Homeostasis
  • Protein Ubiquitination
  • SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
  • Post-translational Protein Modification
  • Iron Ion Homeostasis
  • Positive Regulation Of Cellular Protein Catabolic Process
Pathways
  • Association of TriC/CCT with target proteins during biosynthesis
  • Neddylation
  • Iron uptake and transport
  • Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
  • Blood protein levels ( 28240269)
  • Estimated glomerular filtration rate in non-diabetics ( 31451708)
  • Red blood cell count ( 32888494)
Interacting Genes 11 interacting genes: CITED2 CSNK2B DCTN1 EP300 IREB2 LINC00839 NABP2 ORC4 PLK1 SKP1 SNCA
Entrez ID 26234
HPRD ID 05739
Ensembl ID ENSG00000118564
Uniprot IDs Q9UKA1
PDB IDs 3U9J 3U9M 3V5X 3V5Y 3V5Z 6VCD
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025