Wiki-Pi
About
Search
Browse
People
Updates
Search
SUZ12
Description
SUZ12 polycomb repressive complex 2 subunit
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Nuclear Body
ESC/E(Z) Complex
Molecular Function
RNA Polymerase II Transcription Corepressor Binding
Protein Binding
Chromatin DNA Binding
Methylated Histone Binding
Histone Methyltransferase Activity
Metal Ion Binding
Histone Methyltransferase Activity (H3-K27 Specific)
Biological Process
Spinal Cord Development
Response To Retinoic Acid
Negative Regulation Of Chemokine Production
Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein
Negative Regulation Of Cell Differentiation
Negative Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Epithelial Cell Proliferation
Negative Regulation Of G0 To G1 Transition
Histone H3-K27 Trimethylation
Pathways
PRC2 methylates histones and DNA
Oxidative Stress Induced Senescence
PKMTs methylate histone lysines
SUMOylation of chromatin organization proteins
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6
HCMV Early Events
Drugs
Diseases
GWAS
High chromosomal aberration frequency (chromosome type) (
31586183
)
Hip circumference adjusted for BMI (
25673412
)
Novel Interacting Genes
9 novel interacting genes:
ARHGAP5
CDK5R1
KLRC1
NOL4
NR1D1
PLA2G2A
RBBP4
SLC2A2
TBC1D29P
Interacting Genes
17 interacting genes:
AEBP2
BCL11A
CDK19
CDK8
CREB1
CTCF
EZH2
H1-1
H3-4
LATS2
MED17
MED6
PAXIP1
PJA1
PRDM14
UBE2I
WDR77
Entrez ID
23512
HPRD ID
06949
Ensembl ID
ENSG00000178691
Uniprot IDs
J3QQW9
Q15022
PDB IDs
4W2R
5HYN
5IJ7
5IJ8
5LS6
5WAI
5WAK
5WG6
6B3W
6C23
6C24
6NQ3
Enriched GO Terms of Interacting Partners
?
Tagcloud
?