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UNC13D

Description unc-13 homolog D
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Region
  • Lysosome
  • Late Endosome
  • Cytosol
  • Membrane
  • Weibel-Palade Body
  • Azurophil Granule Lumen
  • Intracellular Membrane-bounded Organelle
  • Recycling Endosome
  • Exocytic Vesicle
Molecular Function
  • Protein Binding
  • Small GTPase Binding
  • Metal Ion Binding
Biological Process
  • Granuloma Formation
  • Germinal Center Formation
  • Phagocytosis
  • Regulation Of Mast Cell Degranulation
  • Neutrophil Degranulation
  • Natural Killer Cell Degranulation
  • Positive Regulation Of Exocytosis
  • Defense Response To Virus
  • Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
  • Positive Regulation Of Regulated Secretory Pathway
Pathways
  • Neutrophil degranulation
Drugs
Diseases
  • Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS
  • Apolipoprotein A1 levels ( 32203549)
  • Asthma ( 32296059)
  • Eosinophil counts ( 27863252)
  • Major depressive disorder ( 27777418)
  • Red cell distribution width ( 32888494)
  • Systolic blood pressure ( 30578418)
  • White matter hyperintensity burden ( 25663218)
Interacting Genes 3 interacting genes: LMNA RAB27A RAB27B
Entrez ID 201294
HPRD ID 10598
Ensembl ID ENSG00000092929
Uniprot IDs Q70J99
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025