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NAMPT
Description
nicotinamide phosphoribosyltransferase
Image
GO Annotations
Cellular Component
Cytosol
Nuclear Speck
Cell Junction
Extracellular Exosome
Molecular Function
Nicotinate-nucleotide Diphosphorylase (carboxylating) Activity
Cytokine Activity
Protein Binding
Identical Protein Binding
Nicotinamide Phosphoribosyltransferase Activity
Biological Process
Signal Transduction
Cell-cell Signaling
Circadian Rhythm
Positive Regulation Of Cell Population Proliferation
Insulin Receptor Signaling Pathway
Circadian Regulation Of Gene Expression
NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process
Adipose Tissue Development
Pathways
BMAL1:CLOCK,NPAS2 activates circadian gene expression
Nicotinamide salvaging
Drugs
GMX1777
Daporinad
Diseases
GWAS
Grapefruit juice consumption (
31046077
)
Novel Interacting Genes
1 novel interacting genes:
LOX
Interacting Genes
5 interacting genes:
ADORA2A
AKT2
FANCA
GGT1
USP49
Entrez ID
10135
HPRD ID
09938
Ensembl ID
ENSG00000105835
Uniprot IDs
A0A024R718
P43490
PDB IDs
2E5B
2E5C
2E5D
2GVG
2GVJ
3DGR
3DHD
3DHF
3DKJ
3DKL
4JNM
4JR5
4KFN
4KFO
4KFP
4L4L
4L4M
4LTS
4LV9
4LVA
4LVB
4LVD
4LVF
4LVG
4LWW
4M6P
4M6Q
4N9B
4N9C
4N9D
4N9E
4O0Z
4O10
4O12
4O13
4O14
4O15
4O16
4O17
4O18
4O19
4O1A
4O1B
4O1C
4O1D
4O28
4WQ6
5KIT
5LX3
5LX5
5NSD
5U2M
5U2N
5UPE
5UPF
5WI0
5WI1
6ATB
6AZJ
6B75
6B76
6E68
6PEB
Enriched GO Terms of Interacting Partners
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