| APOA5 |
apolipoprotein A5 |
- PPARA activates gene expression
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- Post-translational protein phosphorylation
- Assembly of active LPL and LIPC lipase complexes
- Chylomicron remodeling
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- Hyperlipoproteinemia, type V
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| CDK1 |
cyclin dependent kinase 1 |
- MAPK3 (ERK1) activation
- E2F-enabled inhibition of pre-replication complex formation
- Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
- Golgi Cisternae Pericentriolar Stack Reorganization
- Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes
- APC/C:Cdc20 mediated degradation of Cyclin B
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Regulation of APC/C activators between G1/S and early anaphase
- Phosphorylation of the APC/C
- Phosphorylation of Emi1
- Condensation of Prophase Chromosomes
- MASTL Facilitates Mitotic Progression
- Resolution of Sister Chromatid Cohesion
- Condensation of Prometaphase Chromosomes
- Regulation of PLK1 Activity at G2/M Transition
- Activation of NIMA Kinases NEK9, NEK6, NEK7
- Initiation of Nuclear Envelope (NE) Reformation
- Nuclear Pore Complex (NPC) Disassembly
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Depolymerisation of the Nuclear Lamina
- Anchoring of the basal body to the plasma membrane
- MAPK6/MAPK4 signaling
- Ovarian tumor domain proteases
- TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
- Regulation of TP53 Degradation
- Mitotic Prophase
- G1/S-Specific Transcription
- Cyclin A/B1/B2 associated events during G2/M transition
- Cyclin A/B1/B2 associated events during G2/M transition
- G2/M DNA replication checkpoint
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
- The role of GTSE1 in G2/M progression after G2 checkpoint
- AURKA Activation by TPX2
- Transcriptional regulation by RUNX2
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- Indirubin-3'-Monoxime
- Olomoucine
- Hymenialdisine
- SU9516
- Alvocidib
- Alsterpaullone
- AT7519
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| CHM |
CHM Rab escort protein |
- TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
- RAB geranylgeranylation
- RAB GEFs exchange GTP for GDP on RABs
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- Choroideremia (CHM); Tapetochoroidal dystrophy
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| EEA1 |
early endosome antigen 1 |
- Toll Like Receptor 9 (TLR9) Cascade
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- Inositol 1,3-Bisphosphate
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| GLP1R |
glucagon like peptide 1 receptor |
- Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
- Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
- G alpha (s) signalling events
- Glucagon-type ligand receptors
- ADORA2B mediated anti-inflammatory cytokines production
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- Glucagon recombinant
- Exenatide
- Liraglutide
- Albiglutide
- Dulaglutide
- Lixisenatide
- Semaglutide
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| PIK3CB |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
- PI3K Cascade
- IRS-mediated signalling
- GPVI-mediated activation cascade
- PIP3 activates AKT signaling
- Synthesis of PIPs at the plasma membrane
- Downstream signal transduction
- PI3K/AKT activation
- Downstream TCR signaling
- Role of phospholipids in phagocytosis
- Tie2 Signaling
- Constitutive Signaling by Aberrant PI3K in Cancer
- DAP12 signaling
- Role of LAT2/NTAL/LAB on calcium mobilization
- Nephrin family interactions
- VEGFA-VEGFR2 Pathway
- VEGFA-VEGFR2 Pathway
- Interleukin-3, Interleukin-5 and GM-CSF signaling
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
- RET signaling
- Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
- Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
- Interleukin receptor SHC signaling
- Regulation of signaling by CBL
- Regulation of signaling by CBL
- Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants
- Signaling by PDGFRA extracellular domain mutants
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| PRIM1 |
DNA primase subunit 1 |
- Inhibition of replication initiation of damaged DNA by RB1/E2F1
- Polymerase switching on the C-strand of the telomere
- Telomere C-strand synthesis initiation
- DNA replication initiation
- Activation of the pre-replicative complex
- Polymerase switching
- Removal of the Flap Intermediate
- Processive synthesis on the lagging strand
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| RABAC1 |
Rab acceptor 1 |
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| REEP5 |
receptor accessory protein 5 |
- Olfactory Signaling Pathway
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| RIN1 |
Ras and Rab interactor 1 |
- RAB GEFs exchange GTP for GDP on RABs
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| RIN2 |
Ras and Rab interactor 2 |
- RAB GEFs exchange GTP for GDP on RABs
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- Macrocephaly, alopecia, cutis laxa, and scoliosis; MACS syndrome
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| RIN3 |
Ras and Rab interactor 3 |
- RAB GEFs exchange GTP for GDP on RABs
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| SGSM3 |
small G protein signaling modulator 3 |
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| SUN2 |
Sad1 and UNC84 domain containing 2 |
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| TBC1D15 |
TBC1 domain family member 15 |
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| TBC1D17 |
TBC1 domain family member 17 |
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| TFRC |
transferrin receptor |
- Golgi Associated Vesicle Biogenesis
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
- Transferrin endocytosis and recycling
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