| APP |
amyloid beta precursor protein |
- Platelet degranulation
- ECM proteoglycans
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- G alpha (q) signalling events
- G alpha (i) signalling events
- Lysosome Vesicle Biogenesis
- Formyl peptide receptors bind formyl peptides and many other ligands
- TAK1 activates NFkB by phosphorylation and activation of IKKs complex
- The NLRP3 inflammasome
- Advanced glycosylation endproduct receptor signaling
- Advanced glycosylation endproduct receptor signaling
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- Post-translational protein phosphorylation
- TRAF6 mediated NF-kB activation
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Purinergic signaling in leishmaniasis infection
- Amyloid fiber formation
|
- Deferoxamine
- Aluminium
- Zinc
- L-methionine (R)-S-oxide
- Resveratrol
- Phenserine
- Tiomolibdate ion
- CAD106
- Mito-4509
- Dimercaprol
- Copper
- Florbetaben (18F)
- Florbetapir (18F)
- Flutemetamol (18F)
|
|
| LRPAP1 |
LDL receptor related protein associated protein 1 |
|
|
|
| PABPC1 |
poly(A) binding protein cytoplasmic 1 |
- L13a-mediated translational silencing of Ceruloplasmin expression
- Deadenylation of mRNA
- AUF1 (hnRNP D0) binds and destabilizes mRNA
- Translation initiation complex formation
- Regulation of expression of SLITs and ROBOs
- Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
|
|
|
| PLAT |
plasminogen activator, tissue type |
- Signaling by PDGF
- Dissolution of Fibrin Clot
|
- Urokinase
- Aminocaproic Acid
- Ibuprofen
- Iloprost
- Human C1-esterase inhibitor
- 5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID
- Dexibuprofen
- Conestat alfa
|
|
| PLAUR |
plasminogen activator, urokinase receptor |
- Attachment of GPI anchor to uPAR
- Neutrophil degranulation
- Dissolution of Fibrin Clot
|
- Alteplase
- Urokinase
- Reteplase
- Anistreplase
- Tenecteplase
- WX-UK1
|
|
| SERPINE1 |
serpin family E member 1 |
- Platelet degranulation
- BMAL1:CLOCK,NPAS2 activates circadian gene expression
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
- ECM proteoglycans
- Dissolution of Fibrin Clot
|
- Alteplase
- Urokinase
- Reteplase
- Anistreplase
- Tenecteplase
- Drotrecogin alfa
- Troglitazone
- Fibrinolysin
- Copper
|
|